'Bit score' diaporamas de présentation

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1.5k views • 129 slides

Iterative homology searching using PSI-BLAST, scoring statistics and performance evaluation

C. E. N. T. E. R. F. O. R. I. N. T. E. G. R. A. T. I. V. E. B. I. O. I. N. F. O. R. M. A. T. I. C. S. V. U. Introduction to bioinformatics 2008 Lecture 10. Iterative homology searching using PSI-BLAST, scoring statistics and performance evaluation. Today:

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Introduction to Bioinformatics

Introduction to Bioinformatics. Lecture 12 : Iterative h omology searching and Protein Structure-Function Relationships Centre for Integrative Bioinformatics VU (IBIVU). PSI ( Position Specific Iterated ) BLAST. basic idea use results from BLAST query to construct a profile matrix

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Genome Analysis 2007 Lecture 7

C. E. N. T. E. R. F. O. R. I. N. T. E. G. R. A. T. I. V. E. B. I. O. I. N. F. O. R. M. A. T. I. C. S. V. U. Genome Analysis 2007 Lecture 7. Iterative h omology searching (PSI-BLAST). PSI ( Position Specific Iterated ) BLAST. basic idea

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Introduction to bioinformatics 2007 Lecture 13

C. E. N. T. E. R. F. O. R. I. N. T. E. G. R. A. T. I. V. E. B. I. O. I. N. F. O. R. M. A. T. I. C. S. V. U. Introduction to bioinformatics 2007 Lecture 13. Iterative h omology searching,. PSI ( Position Specific Iterated ) BLAST. basic idea

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Sequence Similarity Searches

Sequence Similarity Searches. Subtitle. Three key questions. Query? Purpose? Database?. BLAST. >gi|77630012|ref|ZP_00792598.1| COG0442: Prolyl-tRNA synthetase [Yersinia pseudotuberculosis IP 31758] Length=572 Score = 1013 bits (2619), Expect = 0.0, Method: Composition-based stats.

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DNA Sequence Analysis

DNA Sequence Analysis. Broad and Long Term Objective. To characterize a single clone from an Emiliania huxleyi cDNA library using sequence analysis. Research Plan. Preparation of Competent Cells and Bacterial Transformation. Growth of Transformant and Plasmid MiniPrep. Cycle Sequencing.

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Motif finding methods and algorithms

Motif finding methods and algorithms. Given a set of n promoters of n coregulated genes, find a motif common to the promoters. Both the PWM and the motif sequences are unknown. Common methods: 1 . Enumeration: Simplest case: look at the frequency of all n-mers

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BLAST:

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Bioinformatics

Bioinformatics. Ayesha M. Khan 21 st March, 2012. Some statistics of local sequence comparison (BLAST).

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