Catalytic domains - PowerPoint PPT Presentation

Growth Factors and Receptor Tyrosine Kinases

Growth Factors and Receptor Tyrosine Kinases. RTK’s--How do they work? EGFR signaling and ras MAP k inase cascades PI3K, PKB, PLC g PTPs (Protein Tyrosine Phosphatases). Epidermal growth factor. Neurotrophic growth factor (NGF) isolated from mouse

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Protein Motifs

Protein Motifs. Protein Phosphatases Roy Poh Feb 08. Phosphatase. Enzymes that removes a phosphate group from its substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group (dephosphorylation).

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119

A. Fig A. : Domain structure organisation of LmPDI analysed using CDD database. a and a’ represents the catalytic domains (CGHC); b-b’ the non catalytic domains; and c, the acidic terminal extension with KDEL ER localization signal. B. 1. 26. 119. 145. 219. 231. 333. 355. 454. 477. a.

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