Causal variants - PowerPoint PPT Presentation

Estimating “Heritability” using Genetic Data

Estimating “Heritability” using Genetic Data. David Evans University of Queensland. The Majority of Heritability for Most Complex Traits and Diseases is Yet to Be Explained. Maher (2009) Nature. Places the Missing Heritability Could be Hiding.

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663 views • 30 slides

Assumptions in using SNPs to estimate trait heritability among ‘ unrelated ’ individuals

Assumptions in using SNPs to estimate trait heritability among ‘ unrelated ’ individuals. Matthew Keller Teresa de Candia University of Colorado at Boulder. Outline. Overview of estimating genetic variance tagged by SNPs how it works: HE-regression example how to interpret SNP h 2

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255 views • 23 slides

GeneGrid finding disease causing variants in NGS data

GeneGrid finding disease causing variants in NGS data. Claudia Gugenmus Genomatix Software GmbH Bayerstrasse 85a. 80335 Munich, Germany http://www.genomatix.com. Motivation. Whole genome/ exome sequencing.

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316 views • 13 slides

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