Endosome - PowerPoint PPT Presentation

Cloning Rab5WT and Rab5 Mutants to Study the Endocytic Pathway Involving TGF-  Receptor and Rin1

Cloning Rab5WT and Rab5 Mutants to Study the Endocytic Pathway Involving TGF-  Receptor and Rin1. Min Kang Colicelli Lab, UCLA. Growth factors. RTK. RTK. RAS. Adaptor. GEFs. GAPs. GTP. Rab5. Recycling endosome. Other Effectors. Early endosome. RAF. PI3K. RIN1.

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Internalisation

Ligand. P. P. P. GRK. 1. GRK. 2. β -arrestine. P. P. P. P. CCP. P. P. β -arrestine. β -arrestine. Rab4 (fast). Recycling. 3. 4. Internalisation. Rab11 (slow). Golgi complex. Early /sorting endosome. GASP Rab7. 5. Endoplasmic reticulum. Rab11. Late endosome.

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120 views • 1 slides

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