Fine scale mapping - PowerPoint PPT Presentation

FINE SCALE MAPPING

FINE SCALE MAPPING. ANDREW MORRIS Wellcome Trust Centre for Human Genetics March 7, 2003. Outline. Introduction: fine scale mapping using high-density SNP haplotype data. Bayesian framework. Gene trees and the coalescent process. Genetic heterogeneity and shattered gene trees.

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A multi-phenotype protocol for fine scale mapping of QTL in outbred heterogeneous stock mice

A multi-phenotype protocol for fine scale mapping of QTL in outbred heterogeneous stock mice. LC Solberg , C Arboledas, P Burns, S Davidson, G Nunez, A Taylor, W Valdar , R Deacon, D Bannerman, W Cookson, D Gauguier, JNP Rawlins, R Mott, J Flint

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INTRODUCTION

S. Detection of Structural Variants. Sample Reads. Insertion. Sample Reads. b. a. Deletion. Reference. a. b. Reference. (a) Deletion. (b) Insertion. Sample Reads. Sample Reads. Insertion. A’. A’’. d. Sample Reads. Sample Reads. d. 1. 2. b. a. a. b. 2’. Reference.

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