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KRAS Status in Response to Cetuximab

KRAS Status in Response to Cetuximab. Retrospective analysis of CRYSTAL [1] PFS and ORR benefit of FOLFIRI + cetuximab only observed in mCRC patients with wild-type KRAS. E Idelevich, 2011. * P = .017; † P = .75; ‡ P = .0025. 1. Van Cutsem E, et al. ASCO 2008. Abstract 2.

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Conflicts of interest

Final Results from Study 181: Randomized Phase 3 Study of FOLFIRI +/- Panitumumab for the Treatment of 2 nd ‑line Metastatic Colorectal Cancer. A. Sobrero , 1 M. Peeters, 2 T. Price, 3 Y. Hotko, 4 A. Cervantes, 5 M. Ducreux, 6 T. André, 7 E. Chan, 8 F. Lordick 9 Y. Tian, 10 R. Sidhu 10

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242 views • 14 slides

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