Foxm1 - PowerPoint PPT Presentation

Supplementary Figure S6. Effects of OHT and ectopic expression of FOXM1 and ERα in the

MDA-MB-231. A. h. OHT:. 0. 4. 8. 24. 48. FOXM1. PLK. CDC25b. ER α. Tubulin. B. C. MDA-MB-231. MDA-MB-231. ER α :. 0. µg. 4. 0. µg. 2. 6. FOXM1:. 3. FOXM1. ER α. ER α. FOXM1. Cyclin D1. Cyclin D1. pS2. pS2. Tubulin. Tubulin.

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Normalised mRNA level

A. B. Foxm1 mRNA. WT MEFs. Foxm1 -/- MEFs. ***. FOXM1. Normalised mRNA level. PLK. β - Tubulin. WT MEFs. Foxm1 -/- MEFs. C. FOXM1. Merge. DAPI. WT MEFs. Foxm1 -/- MEFs. D. **. **. **. ***. ***. ***. WT MEFs. % Cell Viability at 24 h. **. **. Foxm1 -/- MEFs.

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FOXM1

A. Foxm1 -/- MEFs. WT MEFs. Foxm1 mRNA. Brip1 mRNA. Plk mRNA. FOXM1 . **. **. *. ***. BRIP1 . Normalised mRNA level. PLK . β - Tubulin. WT MEFs. WT MEFs. WT MEFs. Foxm1 -/- MEFs. Foxm1 -/- MEFs. Foxm1 -/- MEFs. B. WT MEFs. Foxm1 -/- MEFs. Epirubicin (0.1 µM):.

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