Gene filtering - PowerPoint PPT Presentation

Probe analysis and data preprocessing

Probe analysis and data preprocessing. Affymetrix Probe level analysis Normalization Constant, Loess, Rank invariant, Quantile normalization Expression measure MAS 4.0, LI-Wong ( dChip ), MAS 5.0, RMA Background adjustment PM-MM, PM only, RMA, GC-RMA Statistical analysis of cDNA array

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David Elashoff UCLA Department of Biostatistics

Impact of the Choice of Expression Metric on the Standard Statistical Analysis of Oligonucleotide Microarray Data. David Elashoff UCLA Department of Biostatistics. Outline. Introduction to Affymetrix Microarrays Data Preprocessing Methods Within metric comparisons

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