'Gene rearrangement' diaporamas de présentation

Chapter 43

Chapter 43. The Immune System. Overview: Reconnaissance, Recognition, and Response An animal must defend itself From the many dangerous pathogens it may encounter in the environment Two major kinds of defense have evolved that counter these threats Innate immunity and acquired immunity.

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T Cell Receptor & T Cell Development

T Cell Receptor & T Cell Development. Questions for the next 2 lectures : How do you generate a diverse T cell population with functional TCR rearrangements? How do you generate a T cell population that is self-MHC restricted? How do you ensure that those diverse T cell

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Ch4. Antibody Structure and the Generation of B-cell diversity

Ch4. Antibody Structure and the Generation of B-cell diversity. B-Cell Receptor (BCR). Immunoglobulin(Ig), antibody specificity: one antibody for one antigen or a few different antigens diversity: as high as 10 16 of antibody repertoire; in practice about 10 9

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Lecture 8 The Development of Lymphocytes

Lecture 8 The Development of Lymphocytes. Core content. Students should know:. T cell receptor gene rearrangement and lineage commitment preTCR Positive selection Negative selection Changes in surface phenotype during T cell maturation in thymus.

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Lymphocyte Development and Antigen Receptor Gene Rearrangement

Lymphocyte Development and Antigen Receptor Gene Rearrangement. Chapter 8. Stages of lymphocyte maturation. Pluripotent stem cells give rise to distinct B and T lineages. Epigenetics, MicroRNAs, and Lymphocyte Development.

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T CELL BIOLOGY T cell development T cell activation T cell responses

Lecture Blocks. T CELL BIOLOGY T cell development T cell activation T cell responses. SPECIAL CELLS, PLACES AND THINGS NK Cells, Mucosa, Cytokines. IMMUNE REGULATION Regulation of Immunity Infections and vaccines Autoimmunity/Tolerance Immunology of Pregnancy. Course Material.

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Transposon

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ANTIBODY DIVERSITY II

ANTIBODY DIVERSITY II. Macfarlane Burnet (1956 - 1960) C LONAL SELECTION THEORY. Antibodies are natural products that appear on the cell surface as receptors and selectively react with the antigen Lymphocyte receptors are variable and carry various antigen-recognizing receptors

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Introduction to Leukemia

Introduction to Leukemia. Definition Historic Perspective Etiology and Risk Factors Incidence Classification Comparison of Acute and Chronic Leukemia. Leukemia Definition

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Introduction to Leukemia

Introduction to Leukemia. Definition Historic Perspective Etiology and Risk Factors Incidence Classification Comparison of Acute and Chronic Leukemia. Leukemia Definition

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B Cell Development

Assignment: Chapter 4 (Skip Figs. 4.6, 4.12). B Cell Development. Learning Objectives for Lecture 11 Discover how lymphoid stem cells become B cells destined to make antibodies Understand the importance of Ig gene rearrangement Appreciate mechanisms leading to B-cell leukemias. Notes

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Immunoglobulin Gene Rearrangement

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Word morphology

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