Analyzing and Engineering Genes. Chapter 19. Analyzing and Engineering DNA. Genetic engineering- Manipulation of DNA sequences in organisms Recombinant DNA technology used to engineer genes Biotechnology -the manipulation of organisms to create products or cure diseases
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Genome Engineering. Why engineer the genome?. Eliminate gene activity -test loss of function phenotype -spatial control of gene loss(mosaic analysis) -temporal control of gene loss. Control gene expression -investigation of gene function -structure/function analysis of gene activity
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Genetics of Vascular Diseases Jake Lusis 3-730 MRL Jlusis@mednet.ucla.edu. Carl Miller, ~1938, Oslo County Hospital, Norway. Inheritance of: Cholesterol level (mg/dl): Tendon xanthomas: Early coronary artery disease (under 55 years of age):. 330 210. 210. 200. 210. 180. 430. 410.
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