'Glycogen phosphorylase' diaporamas de présentation

Carbohydrates

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glycogen metabolism

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Glycogen Metabolism

Glycogen Metabolism. Introduction. Storage Polysaccharides. Why Polysaccharides?. Rapid mobilization Support anaerobic metabolism Animals cannot convert fats to glucose precursors. Why Polymers?. Osmotic Problem!. Glycogen Metabolism. Glycogen Breakdown. Storage Tissues.

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Metabolism as a three dimensional meshwork

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Glucose homeostasis

The Pancreas. Glucose homeostasis. Pancreatic Hormones, Insulin & Glucagon Regulate Metabolism. Actions of insulin and glucagon. Insulin Signal of feeding. Target tissues: liver, adipose skeletal muscle Affects metabolism of: carbohydrates, lipids proteins Actions are anabolic.

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Coordinated regulation of glycolysis/gluconeogenesis

Coordinated regulation of glycolysis/gluconeogenesis. Regulation of glycolysis. Hexokinase Phosphofructokinase-1 Pyruvate kinase. Hexokinase. There are four isozymes (I, II, III and IV) of hexokinase encoded by four different genes.

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Biochemical Mechanism of Magnesium

Biochemical Mechanism of Magnesium. Mark H. Whitney, Jeffrey S. Knott, and Jayne L. Kalbfleisch. Central Nervous System. STRESS. CRF - Corticotropin Releasing Factor ACTH -Adrenocorticotrophic Hormone. Adapted from Classen and Porta, 1996. Central Nervous System. STRESS. Hypothalamus.

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Chapter 15

Chapter 15. Principles of Metabolic Regulation: Glucose and Glycogen Part 2. Learning Goals: Know. How Insulin works to affect genes for gluconeogenesis. How glycogen breakdown works. How liver cells get glycogen converted to glucose not in the presence of hexokinase. Why?

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Exam III Review 11/19/2009

Exam III Review 11/19/2009. Exam 3 Review. Chapters: 12 Enzyme Kinetic Mechanisms 8 Carbohydrates 14 Metabolism 15 Glucose Metabolism 16 Glycogen Metabolism and Gluconeogenesis 17 Primarily pyruvate dehydrogenase. The Citric acid cycle.

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Bioc 460 Spring 2008 - Lecture 34 (Miesfeld)

Carbohydrate Metabolism 2: Glycogen degradation, glycogen synthesis, reciprocal regulation of glycogen metabolism. Bioc 460 Spring 2008 - Lecture 34 (Miesfeld). Glycogen phosphorylase enzyme is a dimer that is regulated by both phosphorylation and allostery.

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Structure of glycogen

Structure of glycogen. * Glycogen: branched-chain homopolysaccharide made of ?-D-glucose linked by ?-1,4 linkage. After every 8-10 glucose residues there is a branch containing ?-1,6 linkage.

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PRINCIPLES OF METABOLIC REGULATION: GLUCOSE AND GLYCOGEN

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Studing of biosynthesis and catabolism of glycogen . Regulation of glycogen metabolism.

Studing of biosynthesis and catabolism of glycogen . Regulation of glycogen metabolism. GLYCOGEN SYNTHESIS AND DEGRADATION. In the well-fed state the glucose after absorption is taken by liver and deposited as a glycogen

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Glycogen Metabolism

Glycogen Metabolism. Glycogen is a polymer of glucose residues linked by a (1 ? 4) glycosidic bonds, mainly a (1 ? 6) glycosidic bonds, at branch points. Glucose is stored as glycogen predominantly in liver and muscle cells. Glycogenesis and glycogenolysis.

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GLYCOGEN BREAKDOWN AND SYNTHESIS ARE RECIPROCALLY REGULATED

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Carbohydrate Metabolism: Gluconeogenesis

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Glycogen Metabolism

Glycogen Metabolism. Before we get to glycogen: Dietary sugars. Glycogen. Branched every 8-12 residues Up to 50,000 or so residues total. Amylopectin : branch every 25 residues. Glycogen Synthesis and Breakdown . Glycogen synthesis and breakdown are both controlled by hormones

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TRANSPORT OF MONOSACCARIEDS DR SAMEER FATANI

TRANSPORT OF MONOSACCARIEDS DR SAMEER FATANI. TRANSPORT OF MONOSACCHARIDES Digestion of di- and polysaccharides results in the following MONOSACCHARIDES: D- glucose D- galactose And D- fructose Absorption of these Monosacchardies is carried out by CARRIER-MEDIATED PROCESSES

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Changing the rate of enzyme reactions

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S645

PYGM. GYS2. PYGL. PYGB. GYS1. S11. S641. S82. S15. S15. S15. S8. S641. S8. S645. S645. GSK3 b. PKA. p38 a MAPK. PHK g 1. CK1. MAPKAPK2. Grk3. DYRK2. DYRK1B. PASK. AMPKa 1. DYRK1A. Glycogen Regulation. AMP. cAMP. Ca 2+. Glycogen Degradation. PYGM. GYS2. PYGL.

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