'Histone acetylation' diaporamas de présentation

Canadian Bioinformatics Workshops

Canadian Bioinformatics Workshops. www.bioinformatics.ca. Module #: Title of Module. 2. Canadian Bioinformatics Workshops 2009 Module 3 Inferring Regulatory Mechanisms Governing Sets of Genes Wyeth W. Wasserman University of British Columbia. www.cisreg.ca. Module 3: Overview.

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Canadian Bioinformatics Workshops

Canadian Bioinformatics Workshops. www.bioinformatics.ca. Canadian Bioinformatics Workshops 2008 Inferring Regulatory Mechanisms Governing Sets of Genes Wyeth W. Wasserman University of British Columbia. www.cisreg.ca. Co-Expressed. Negative Controls.

1.42k views • 87 slides

A b o u t O M IC S Group

A b o u t O M IC S Group.

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10-31-2011 Gene expression in eukaryotes 1. Eukaryotic RNA polymerases

10-31-2011 Gene expression in eukaryotes 1. Eukaryotic RNA polymerases 2. Regulation of eukaryotic RNP 3. Hormonal regulation 4. Histone acetylation. Special features of eukaryotic gene expression 1. Complex transcriptional control 2. RNA processing

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Chromatin Modification

Chromatin Modification. Reading Seminar in Computational Biology Naomi Habib 5.1.2006. Chromatin Structure. Nucleosome (histone octamer wrapped with 146 bp of DNA). Chromatin Roles. Compactization Packing ~2 meters of DNA in to a ~10 micron diameter nucleus.

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MECHANISMS OF AGE-RELATED COGNITIVE CHANGE AND TARGETS FOR INTERVENTION: EPIGENETICS

MECHANISMS OF AGE-RELATED COGNITIVE CHANGE AND TARGETS FOR INTERVENTION: EPIGENETICS. MADIHAH MOHAMAD, EIZZATI ARIPIN, SITI ZULAIHA ABU BAKAR. AGING AND EPIGENETIC. Changes- cognitive fx , brain anatomy, physiology and neurochemistry

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The control of gene expression by chromatin remodeling

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Controlling Chromatin Structure

Controlling Chromatin Structure. Why? It is related to gene expression and regulation. Transcription. in vitro in vivo. DNA TFs RNA polymerase nucleosomes. DNA TFs RNA polymerase. Model ?. 1-Equilibrium model: prokaryotes ( limited energy)

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The Necessity For DNA Condensation

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Organization of the eukaryotic genomes

Organization of the eukaryotic genomes. Chromatin structure Genome organization. Why do eukaryotes need to form chromatin? Levels of packing: - role of histones - nucleosomes Euchromatin and heterochromatin. Genome organization. Prokaryotes Most genome is coding

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High-resolution genome-wide mapping of histone modifications

High-resolution genome-wide mapping of histone modifications. Tae-young Roh*, Wing Chi Ngau+, Kairong Cui*, David Landsman+ & Keji Zhao* *Laboratory of Molecular immunology, National heart blood and lung institute NIH

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Polytene Chromosomes of D. melanogaster

Polytene Chromosomes of D. melanogaster. Electron Micrograph of a Single Chromatid of a Mitotic Chromosome. Electron Micrographs of Chromatin Strands Before and After Treatment. Micrococcal Nuclease Digestion of Chromatin. Sedimentation of Nucleosomes. Properties of Histones.

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Controlling Chromatin Structure

Controlling Chromatin Structure. Chapter 30. 30.2 Chromatin Can Have Alternative States. Chromatin structure: is stable cannot be changed by altering the equilibrium of transcription factors and histones. Figure 30.2. 30.3 Chromatin Remodeling Is an Active Process.

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Decreased Neurogenesis (Dentate Gyrus)

REGULATION OF HISTONE ACETYLATION IN THE HIPPOCAMPUS OF CHRONICALLY STRESSED RATS: A POTENTIAL ROLE OF SIRTUINS. In Hippocampus Chronic Variable Stress (CVS) Induces :. Suppression of Synaptic Plasticity (CA1). Decreased Neurogenesis (Dentate Gyrus). Atropy in Apical Dendrites (CA3).

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Announcements

Announcements. Homework 8 due next Wednesday Clicker quiz on Monday, covers Chapter 18 (key terms 11) Next exam: April 18 (Wednesday). BIO 304 Lecture 27. Positive control of the lac operon. The trp operon. Attenuation at the trp operon. Comparison of lac and trp operons.

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Immunoglobulin V regions diversify by gene conversion in DT40 cells

? V ? V ? V ? V V J C ?1. ? V. ? V ? V ? V ? V V * J C ?1. V. V *. Immunoglobulin V regions diversify by gene conversion in DT40 cells. Able to assay of sIgM+ status by flow cytometry.

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Histone Acetyltransferase Pathway

Histone acetylation occurs in a specific lysine residue in the N-terminal basic amino acid concentration region of the core histone, and the acetyl group of acetyl-CoA is transferred to NH of lysine to neutralize a positive charge. Histone acetylation levels are determined by both histone acetyltransferase and histone deacetylase.

11 views • 1 slides

Histone Acetyltransferase Pathway

Histone acetylation occurs in a specific lysine residue in the N-terminal basic amino acid concentration region of the core histone, and the acetyl group of acetyl-CoA is transferred to NH of lysine to neutralize a positive charge. Histone acetylation levels are determined by both histone acetyltransferase and histone deacetylase.

13 views • 1 slides

Histone Acetyltransferase Pathway

Histone acetylation occurs in a specific lysine residue in the N-terminal basic amino acid concentration region of the core histone, and the acetyl group of acetyl-CoA is transferred to NH of lysine to neutralize a positive charge. Histone acetylation levels are determined by both histone acetyltransferase and histone deacetylase.

16 views • 1 slides