'Housekeeping genes' diaporamas de présentation

Transcription

Transcription. Chapter 8. The Problem. Information must be transcribed from DNA in order function further. REMEMBER: DNA ?RNA?Protein. Tanscription in Prokaryotes. Polymerization catalyzed by RNA polymerase Can initiate synthesis Uses rNTPs Requires a template

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CHAPTER 6. ??????. ?????? RNA ???. ????????? RNA ?????????????????????? DNA ????? RNA ??????? ???? (transcription) ???? RNA ??????????????????????????????????????? RNA ?? ( ??? tRNA, rRNA) ????????????????

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Clustering Gene Expression Data: The Good, The Bad, and The Misinterpreted

Clustering Gene Expression Data: The Good, The Bad, and The Misinterpreted. Elizabeth Garrett-Mayer November 5, 2003 Oncology Biostatistics Johns Hopkins University esg@jhu.edu. Acknowledgements: Giovanni Parmigiani, David Madigan, Kevin Coombs. Data from Garber et al. PNAS (98), 2001.

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Activities of RNA Polymerase

Activities of RNA Polymerase. sequence specific DNA binding -promoters melts DNA to reveal the template strand selects ribonucleotide (not deoxynucleotides) that anneals to template strand polymerizes RNA strand translocates on DNA template, during which it must:

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Human Genetics

Human Genetics. NonAutosomal Inheritance. NonAutosomal Inheritance. X-Linked Dominant X-linked Recessive Y-linked Mitochondial. The Sex Chromosomes . The Sex Chromosomes . There is no universal system; can be either genetic or environmental

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Genotyping The NARSA Collection

Genotyping The NARSA Collection. Barry N. Kreiswirth PHRI . - 8. - 56. - 16. - 16. - 8. - 26. - 84. - 28. - 0. Clinical Relevant Strains. Genotyping Methods. Pulsed-Field Gel Electrophoresis (PFGE) Multilocus Sequence Typing (MLST)

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Chapter 17 Regulation of Gene Expression in Bacteria and Bacteriophages

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HCS 830 Overview Presentation

HCS 830 Overview Presentation. Stress Granules Marcelo Pomeranz. What is a Stress Granule?. Stress Granules are non-membranous mRNPs (Found in Yeast,Protozoa,Metazoa,Plants, *prokaryotes) Range in size from .1 to 2.0um. . Virus= 100nm. Bacteria=1.5um. Plant Cell 15um.

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Flow chart of Affymetrix from sample to information

Flow chart of Affymetrix from sample to information. Functional annotation. Pathway assignment. Co-ordinate regulation. Tissue. Promoter motif commonalities. Output as Affy.chp file. Text. Generate Affy.dat file. Hybridize to Affy arrays. Hyb. cRNA. Self Organized Maps (SOMs).

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Human gene expression and genomic imprinting

Human gene expression and genomic imprinting . Lecture 3.

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Rosalind Elsie Franklin

Rosalind Elsie Franklin. Biophysicist and crystallographer X-ray diffraction images of DNA Tobacco mosaic and polio viruses 1920-1958 (source: wikipedia). A Structural Split in the Human Genome. Clara S. M. Tang and Richard J. Epstein PLoS One (2007) 7:e603 February 13, 2007

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31 Gene regulation in bacteria

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Differential Gene Expression

Differential Gene Expression. Turning Genes on or keeping them off?. Differential Gene Regulation. Transcriptional regulation Post-transcriptional regulation Translational regulation Post-translational regulation. Transcriptional Post-transcriptional Translational Post-translational.

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Genome organisation and evolution

Genome organisation and evolution. Level 3 Molecular Evolution and Bioinformatics Jim Provan. Page and Holmes: Sections 3.1.4/5 and 3.3. Single-copy protein coding genes. Dispersed. Multigene families. Tandemly repeated. Regulatory sequences. Satellite DNA. Tandemly repeated DNA.

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IMG/M and metagenome analysis

IMG/M and metagenome analysis. Natalia Ivanova. MGM Workshop September 18, 2008. Problems of metagenomic data IMG/M features Analysing metagenomic data: flowcharts. Outline. Problems of metagenomic data (metagenomic data is the problem) (see IMG/M -> Using IMG/M -> About IMG/M

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