Lamin - PowerPoint PPT Presentation

Laminopathies

Laminopathies. New Discoveries in “Old” Diseases. Dan Imler, MD. Case Presentation. 13 mo M comes to her PMD’s office Parents Concerns Always has been small (ht and wt) and a poor feeder Has not developed any teeth yet Odd looking nails Always had a strange cry, Dad calls it “Girlie”

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350 views • 17 slides

Nuclear lamins and laminopathies

Nuclear lamins and laminopathies. - What is lamin A ? - LAMINOPATHIES Drug discovery platform: Lamin A and aging Prelamin A processing and drugs acting on it Structure of the platform DIATHEVA’s antibodies unique performance. Version 01-06-11. INDEX. WHAT IS LAMIN A?.

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655 views • 7 slides

Nrf2 (whole tissue)

Nishioka et al. supplementary Figure S1. Nrf2 (whole tissue). 54 kDa. β -actin. Nrf2 (cytosol). 54 kDa. tubulin. Nrf2 (nuclei). 54 kDa. Lamin A. 1.0. Nrf2/Lamin A. 0.5. wild-type sham. wild-type IPC. p21-KO sham. p21-KO IPC. Nishioka et al. supplementary Figure S2.

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122 views • 2 slides

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