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Advanced Medicinal Chemistry

Advanced Medicinal Chemistry. Lecture 3:. Molecular Interactions and Drug Potency. Barrie Martin AstraZeneca R&D Charnwood. Agonists: Measure % Response vs Agonist concentration EC 50 - The agonist concentration that causes 50% of the maximum response. pEC 50 = - log 10 (EC 50 ).

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Log10 ec50 - PowerPoint PPT Presentation

Advanced Medicinal Chemistry