'Ltp' diaporamas de présentation

Inherited Disorders of Human Memory: Mental Retardation Syndromes

Inherited Disorders of Human Memory: Mental Retardation Syndromes. From Mechanisms of Memory by J. David Sweatt, Ph.D. Ras. R 2. R 4. Grb. R 3. R 1. SOS. PKC. AC. GEF. G Protein. PKA. Ca 2+. Ca 2+. NO. Raf1. NF1. Rap. B-Raf. NF1 GAP. MEK1/2. ERK1/2. RSK2. MAPs.

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LINKS BETWEEN LTP AND LEARNING AND MEMORY Does LTP = learning? Physiological -- cognitive

LINKS BETWEEN LTP AND LEARNING AND MEMORY Does LTP = learning? Physiological -- cognitive. Evidence 1. Molecular approaches relating LTP to learning 2. Electrophysiological approaches to relating LTP to learning. 1. MOLECULAR APPROACHES.

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The Time Machine:

The Time Machine:. Transforming Molecular Signals. into Long-Lasting Synaptic Change. David Santucci Quantitative Biology Bootcamp 2009. Presynaptic Release. Long Term Potentiation. Difference in time scale > 6 orders of magnitude. Induction. Expression. Early. Late.

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Molecular Mechanisms of Learning and Memory Ying Shen, Ph.D.

Molecular Mechanisms of Learning and Memory Ying Shen, Ph.D. Voice: 0571-88208240 Email: yshen@zju.edu.cn Department of Neurobiology Zhejiang University School of Medicine. Plasticity Is Hot!. Aplysia Californica. Eric R. Kandel. Why Aplysia ?. Cellular Mechanism of Habituation.

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Yu Tian Wang Brain Research Centre Faculty of Medicine University of British Columbia

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Previous Experiments

Autophosphorylation at Thr 286 of the ? Calcium-Calmodulin Kinase II in LTP and Learning Karl Peter Giese, Nikolai B. Fedorov, Robert K. Filipkowski, Alcino J. Siilva* Science vol.279, no 5352. pp.870-873. 1998. Previous Experiments. Synaptic Strength Related To Learning/Memory i.e. LTP

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Neural Plasticity: Long-term Potentiation

Neural Plasticity: Long-term Potentiation. Lesson 15. Neural Plasticity. Nervous System is malleable learning occurs Structural changes at synapses Changes in synaptic efficiency Long-term potentiation Long-term depression LTP & LTD throughout brain Many different mechanisms ~.

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Neural Plasticity: Long-term Potentiation

Neural Plasticity: Long-term Potentiation. Lesson 15. Neural Plasticity. Nervous System is malleable learning occurs Structural changes at synapses Changes in synaptic efficiency Long-term potentiation Long-term depression LTP & LTD throughout brain Many different mechanisms ~.

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Xufeng Liu (Jabil) Vishnu Pavan Beeram (Juniper Networks) Igor Bryskin (Huawei Technologies)

d raft-ietf-teas-yang-te-topo-11. Yang Data Model for TE Topologies draft-ietf-teas-yang-te-topo-11 Github: https://github.com/ietf-mpls-yang/te/blob/master/ietf-te-topology.yang. Xufeng Liu (Jabil) Vishnu Pavan Beeram (Juniper Networks) Igor Bryskin (Huawei Technologies)

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Storage of Spatial Information by the Maintenance Mechanism of LTP

Storage of Spatial Information by the Maintenance Mechanism of LTP. Pastalkova et al. Science 313:1141-1144, 2006. Background. There are two (three?) phases of LTP: Short, intermediate, and long Late-term LTP is dependent on gene transcription and protein synthesis. Background.

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Neural Mechanisms of Learning & Memory

Neural Mechanisms of Learning & Memory. Lesson 24. Neural Mechanism of Memory. Short-term Memory Change in neural activity Reverberatory Circuits Long-Term Memory structural change in brain Hebb Synapse simultaneous activity in pre- & postsynaptic neurons ~. Neural Plasticity.

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Long-term Potentiation as a Physiological Phenomenon

Long-term Potentiation as a Physiological Phenomenon. From Mechanisms of Memory by J. David Sweatt, Ph.D. The Entorhinal/Hippocampal System. Entorhinal Cortex. Perforant Pathway. Dentate Gyrus. Stratum Lacunosom Molecular inputs. Mossy Fiber. Lateral Septum, Contralateral CA1.

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BIPN 148 Lecture 14

BIPN 148 Lecture 14. Biochemical Basis of LTP. Spatial learning induces gene expression. Calcium regulation of gene expression. CaM Kinase IV activates CREB. CaM Kinase IV phosphorylates CREB. LTP in dnCKIV mice. dnCaMKIV suppresses fear conditioning. Spatial learning in dnCKIV mice.

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NECIC - Ad Hoc Meeting 19th of October 2006

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Autophosphorylation at Thr 286 of the ? Calcium-Calmodulin Kinase II in LTP and Learning

Autophosphorylation at Thr 286 of the ? Calcium-Calmodulin Kinase II in LTP and Learning. Giese KP, Fedorov NB, Filipkowski RK, Silva AJ., Science Vol. 279, (1998). Mechanisms for generating and maintaining LTP. LTP Induction results in transient increases in intracellular [Ca ++ ].

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Terminals of Lateral Perforant Pathway

Terminals of Lateral Perforant Pathway. Terminals of Medial Perforant Pathway. Cross sections through rat hippocampus stained for cell bodies (left) and for zinc in synaptic terminals (right).

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Lecture 24

Lecture 24. Learning and Memory II. Memories. Long term memory stored in cortex Information is processed for memory storage in other brain regions (i.e hippocampus). Long-term Potentiation. Timothy Bliss and Terje Lomo (1973)

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Plan of my talk Littlest Higgs Model with T-parity Relic abundance of LTP dark matter

Dark matter in the little Higgs model ~ Indirect detection of LTP (Lightest T-odd Particle) dark matter using cosmic positron measurement ~. Collaborated with Masaki Asano (KEK) Nobuchika Okada (KEK) Yasuhiro Okada (KEK). Shigeki Matsumoto (KEK, Theory).

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DTN and NGU

DTN and NGU. Scott Burleigh, NASA/JPL May 16, 2011 Berlin. Overview. DTN LTP insulates DTN from differences between TC and NGU. DTN LTP block aggregation solves the CFDP return traffic problem, but high volume uplink is still important.

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