PRINCIPLES OF BIOCHEMISTRY. Chapter 15 Principles of Metabolic Regulation. 15.1 Regulation of Metabolic Pathways 15.2 Analysis of Metabolic Control 15.3 Coordinated Regulation of Glycolysis and Gluconeogenesis 15.4 The Metabolism of Glycogen in AnimalsBy barto
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Metabolite Kinetics Theoretical Approach. PHM324Y Guest Lecturer Dr. Jasmina Novakovic Apotex Inc, R&D. Learning Objectives. Drug fate Renal and hepatic elimination Drug-metabolite relationships Fundamentals of metabolite kinetics Metabolite concentration versus time profile
Dealing With the Unknown. Metabolomics & Metabolite Atlases. Ben Bowen Pathway Tools Workshop 2010. Acknowledgements. Trent Northen Richard Baran Wolfgang Reindl Do Yup Lee Jane Tanamachi Jill Banfield Curt Fisher Paul Wilmes
Metabolite Kinetics Theoretical Approach. PHM324Y Guest Lecturer Dr. Jasmina Novakovic Apotex Inc, R&D. To be consistent with other slide packs, in this slide pack kfm should be km. Where kfm appears a note identifying the change has been added. Learning Objectives. Drug fate
RNA-metabolite interactions (riboswitches). RNA aptamers. • RNA aptamers are structures that bind specifically to target ligands • Many aptamers have been generated in the laboratory for a wide range of target molecules ( e.g. theophylline aptamer)
Flux. Flux: An Adaptive Partitioning Operator for Continuous Query Systems M.A. Shah, J.M. Hellerstein, S. Chandrasekaran, M.J. Franklin UC Berkeley Presenter: Bradley Momberger. Overview. Introduction Background Experiments and Considerations Conclusion. Introduction.
Flux. Plankse straler. Kevin & Leon. Opgave. T=5506,85°C Bij welke λ is ɸ dan het grootst?. 2200 Watt / Vierkante Meter. 4500 Watt / Vierkante Meter. 6000 Watt / Vierkante Meter. De totale intensiteit per vierkante meter kan dus berekend worden met de formule: ɸ b = f b * (d/R) 2.
FLUX. FLUX Predicates. holds(X, Z) Asserts X in Z knows(X, Z) X is known to be true in Z knows_val(X, V, Z) update(Z1, FAdd, FRemove, Z2) Z2 = Z1 + FAdd – FRemove execute(A, Z1, Z2) Z2 is the state after executing A in Z1. FLUX as a Modeling Language.
Supplemental Figure 2: GC-MS analyses of metabolites produced by CYP703A2 on capric, lauric and myristic acids. Hydroxy-capric acid Metabolite 2. Hydroxy-capric acid Metabolite 3. Hydroxy-capric acid Metabolite 1. Hydroxy-lauric acid Metabolite 1. Hydroxy-lauric acid Metabolite 2.
Scheme for PPARA regulation of gene transcription. FA FA-CoA FA metabolite. Inflammation: ( IL1B , TNFA , IL6, IL12A, MCP1). Amino acid metabolism (GPT). Fatty acid activation: (FCAL2). Corepressor complex HDAC. Coactivator complex HAT. Lipogenesis: (FADS, ME). RXR. RXRL. RXRL.