'Multiple sequence alignments' diaporamas de présentation

Recent Progress in Multiple Sequence Alignments: A Survey

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Pairwise Alignments

Pairwise Alignments. Biology 224 Instructor: Tom Peavy Sept 13 &15. <PowerPoint slides based on Bioinformatics and Functional Genomics by Jonathan Pevsner> . General approach to pairwise alignment. Choose two sequences Select an algorithm that generates a score

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Pairwise Alignments

Pairwise Alignments. Biology 224 Instructor: Tom Peavy Sept 14 &16. <PowerPoint slides based on Bioinformatics and Functional Genomics by Jonathan Pevsner> . General approach to pairwise alignment. Choose two sequences Select an algorithm that generates a score

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Multiple alignment

One of the most essential tools in molecular biology Finding highly conserved subregions or embedded patterns of a set of biological sequences Conserved regions usually are key functional regions, prime targets for drug developments Estimation of evolutionary distance between sequences

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Viral Genomics

Viral Genomics. Allie Evans Colin Lappala Chelsea Layes Sheena Scroggins. The Sorcerer II Global Ocean Sampling Expedition: Northwest Atlantic through Eastern Tropical Pacific Rusch DB, Halpern AL, Sutton G, Heidelberg KB, Williamson S, et al.

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Databases NCBI GenBank- Protein and DNA sequence NCBI Human Map - Human Genome Viewer NCBI Ensembl - Genome browsers for human, mouse, zebra fish, mosquito TIGR - The Institute for Genome Research SwissProt - Protein Sequence and Function ProDom - Protein Domains

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Nuclear receptor ligand-binding domains, looked at from all directions.

Nuclear receptor ligand-binding domains, looked at from all directions. Nuclear receptor function. NR2A2-HN4G. NR2B3-RRXG. NR2A5-HN4 d?. NR2B1-RRXA. NR2B2-RRXB. NR3C1-GCR. NR2A1-HNF4. NR3C4-ANDR. NR3A1-ESTR. NR2C2-TR4. NR3C3-PRGR. NR2C1-TR2-11. NR0B1-DAX1. NR2E1-TLX. NR3A2-ERBT.

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Multiple sequence alignment

Multiple sequence alignment. Conserved blocks are recognized. Different degrees of similarity are marked. Multiple Sequence Alignment. VTISCTGSSSNIGAG-NHVKWYQQLPG VTISCTGTSSNIGS--ITVNWYQQLPG LRLSCSSSGFIFSS--YAMYWVRQAPG LSLTCTVSGTSFDD--YYSTWVRQPPG

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Molecular basis of evolution.

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Databases NCBI GenBank- Protein and DNA sequence NCBI Human Map - Human Genome Viewer NCBI Ensembl - Genome browsers for human, mouse, zebra fish, mosquito TIGR - The Institute for Genome Research SwissProt - Protein Sequence and Function ProDom - Protein Domains

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Bioinformatics

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Protein purification

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Integration of multiple sources of evidence in clinical classification of VUS

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P rotein domain/family db

P rotein domain/family db. Secondary databases are the fruit of analyses of the sequences found in the primary sequence db Either manually curated (i.e. PROSITE, Pfam, etc.) or automatically generated (i.e. ProDom, DOMO)

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PSI-BLAST and Multiple Sequence Alignments

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Bioinformatics

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What is MAPP/MAPP-MMR?

MAPP and MAPP-MMR m ultivariate a nalysis of p rotein p olymorphisms - m is m atch r epair Helen Stuart, Cardiff. What is MAPP/MAPP-MMR?. In silico evaluation resources that help in determining pathogenicity of missense variants detected in sequencing.

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MCB 5472 Assignment #7: Multiple sequence alignment March 5, 2014

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PipeAlign : A new tool for pretein sequence analysis igbmc.u-strasbg.fr/PipeAlign

PipeAlign : A new tool for pretein sequence analysis http://igbmc.u-strasbg.fr/PipeAlign. Plewniak F, Bianchetti L, Brelivet Y, Carles A, Chalmel F, Lecompte O, Mochel T, Moulinier L, Muller A, Muller J, Prigent V, Ripp R, Thierry JC, Thompson JD, Wicker N, Poch O.

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