'Normal allele' diaporamas de présentation

GENETICS

GENETICS. CONTENTS. 1. Diagnostic techniques, M utations , Chromosome disorders 2 . Mendelian d isorders , Multifactorial inheritance, M itochondrial DNA D isorders 3 . Sex differentiation disorders, Developmental disorders. Diagnostic techniques, Mutations, Chromosome disorders.

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UNIT VI - MENDELIAN GENETICS

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Mendelian Inheritance

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Studying Neuronal Function using the Flies and Mice

Studying Neuronal Function using the Flies and Mice. Why flies? We know a great deal about their simple nervous systems: lineages, expression patterns, patterns of connectivity transcriptional regulation.

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Chapter 9

Chapter 9. Gene Mutations. Objectives. Compare phenotypic consequences of point mutations. Distinguish detection of known mutations from scanning for unknown mutations. Discuss methods used to detect point mutations.

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Meiosis and Human Genetics

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POPULATION GENETICS

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Campbell: Chapter 15 Holtzclaw : pg 108 - 110

Please do the following activities on the student media (Chapter 15): - MP3 tutor: Chromosomal Basis of Inheritance - Activity: Sex-Linked Genes - Activity: Linked Genes and Crossing Over.

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UNIT VI - MENDELIAN GENETICS

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Epistatic Gene Interactions

Epistatic Gene Interactions. Gene interactions occur when two or more different genes influence the outcome of a single trait Most morphological traits (height, weight, color) are affected by multiple genes Epistasis describes situation between various alleles of two genes

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Pedigree Analysis

Pedigree Analysis. Why do Pedigrees?. Punnett squares and chi-square tests work well for organisms that have large numbers of offspring and controlled matings, but humans are quite different: 1. small families. Even large human families have 20 or fewer children.

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Pedigree Analysis

Pedigree Analysis. Why do Pedigrees?. Punnett squares and chi-square tests work well for organisms that have large numbers of offspring and controlled matings, but humans are quite different: 1. small families. Even large human families have 20 or fewer children.

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What if we wanted a lot of human insulin?

Biotechnology. Making microbes work for you! Base pairing between nucleic acids is really useful. What if we wanted a lot of human insulin?. Cell containing gene of interest. Bacterium. 1. Gene inserted into plasmid. Fig. 20-2a. Bacterial chromosome. Plasmid. Gene of interest.

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Lesson Overview

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Figure 20.2

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Legal issues related to genetic diagnostics Genomic Information Non-discrimination Act (GINA) what is covered, what not

Legal issues related to genetic diagnostics Genomic Information Non-discrimination Act (GINA) what is covered, what not risk alleles for Alzheimers disease long-term care insurance adverse selection Patents - theoretical quid pro quo weighing benefits vs harms

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Clinical Genetics

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Measuring Evolution of Populations

Measuring Evolution of Populations. 5 Agents of evolutionary change. Mutation. Gene Flow. Non-random mating. Chemical Changes to DNA. Migration. Sexual Selection. Genetic Drift. Selection. Natural Selection Differential Survival. Small population. Hardy-Weinberg equilibrium.

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Retinoblastoma

Retinoblastoma. by Michele Chasteen. What is Retinoblastoma?. Tumor of the eye that can occur at a high frequency in children and sporadically at an older age. Occurs in hereditary and non-hereditary forms (sporadic). Caused by a deletion on chromosome 13 with a locus of 13q14. The RB gene.

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