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Cholesterol transporters as new therapeutic targets

Cholesterol transporters as new therapeutic targets. Unité de Pharmacologie cellulaire et moléculaire. F. Van Bambeke. Physiological roles of cholesterol. Physical role: structure and functions of membranes. fluidity domains (rafts) protein function (pumps).

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Atherosclerosis

Atherosclerosis. Focal plaques within the intima containing cholesterol and cholesterol esters (CE) Affects large and medium sized arteries Causes coronary heart diseases (CHD) Hypercholesterolemia – high serum cholesterol level Elevated LDL and triglycerides –

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1.43k views • 29 slides

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