'Nucleotide' diaporamas de présentation

Advanced Biochemistry and Chemical Biology CHM4034 Spring 2008

Advanced Biochemistry and Chemical Biology CHM4034 Spring 2008. Dr. Lyons office hours lyons@chem.ufl.edu 846-3392 W 10-11 AM T,R 4:00-5:00 PM Class website http://www.chem.ufl.edu/~lyons/. Monosaccharides are modified. Monosaccharides are modified. Oxidation reduction reactions :

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Sequence analysis

Sequence analysis. How to locate rare/important sub-sequences. Sequence Analysis Tasks. Representing sequence features, and finding sequence features using consensus sequences and frequency matrices Sequence features Features following an exact pattern- restriction enzyme recognition sites

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DNA Metabolism

DNA Metabolism. DNA replication: processes by which copies of DNA molecules are faithfully made. DNA repair: processes by which the integrity of DNA are maintained. DNA recombination: processes by which the DNA sequences are rearranged. Map of the E. coli chromosome.

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DNA repair by:S.Solali

DNA repair by:S.Solali. Types of DNA Damage. Deamination: (C ? U and A? hypoxanthine) Depurination: purine base (A or G) lost T-T and T-C dimers: bases become cross- linked, T-T more prominent, caused by UV light (UV-C (<280 nm) and UV-B (280-320 nm)

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Review: DNA ? RNA ? Protein

Review: DNA ? RNA ? Protein. In a cell, genetic information flows from DNA to RNA in the nucleus and RNA to protein at the ribosome. RNA polymerase. Transcription. Nucleus. DNA. mRNA. Intron. Figure 10.20-1. RNA polymerase. Transcription. Nucleus. DNA. mRNA. Intron. RNA processing.

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Why bother with a new technology?

Why bother with a new technology?. Current (2005) $1.00 per kilobase 20 bp / second 100 Gb / year. NHGRI Goals $ ? 100x, 5yrs $ ? 10,000x, 15yrs. Collins, Morgan, Patrinos (2003). Growth of GenBank. 60. 50. 40. 30. Base pairs of DNA (billions). Sequences (millions). 20. 10. 0.

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Chap. 8A Nucleotides and Nucleic Acids

Chap. 8A Nucleotides and Nucleic Acids. Some Basics Nucleic Acid Structure Nucleic Acid Chemistry Other Functions of Nucleotides. Fig. 8-12. X-ray diffraction pattern of DNA fibers. Intro. to Nucleotides and Nucleic Acids.

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Structure & Function of DNA

By C. Kohn, Waterford WI. Structure & Function of DNA. What are genes?. You now know that genes encode for specific traits like eye color, ear lobes, and milk production. A gene is simply a section of DNA that creates the proteins responsible for a specific trait.

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DNA

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Molecular Evolution with an emphasis on substitution rates

Molecular Evolution with an emphasis on substitution rates. Gavin JD Smith State Key Laboratory of Emerging Infectious Diseases & Department of Microbiology The University of Hong Kong

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Molecular Data

Molecular Data. DNA/RNA Protein Expression Interaction. A sequence. A sequence is a linear set of characters (sequence elements) representing nucleotides or amino acids. http://www.cmu.edu/bio/education/courses/03310/LectureNotes/. Character representation of sequences. DNA or RNA

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Using Network Processors in Genomics

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Frederick Griffith (1928)

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Earth Cycles and Ladder of Life

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Gene Action

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Sequence Alignment

Sequence Alignment. Xuhua Xia xxia@uottawa.ca http://dambe.bio.uottawa.ca. Fundamental concepts. The purpose of sequence alignment: Identification of sequence homology and homologous sites

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KEY CONCEPT Carbon-based molecules are the foundation of life.

KEY CONCEPT Carbon-based molecules are the foundation of life. Many carbon-based molecules are made of many small subunits bonded together and are known as MACROMOLECULES. Four main types of carbon-based molecules or macromolecules are found in living things. Carbohydrates Lipids

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BELL WORK : Use the following words to fill in your bubble map:

BELL WORK : Use the following words to fill in your bubble map:. Adenine (A) Base Cytosine (C) Deoxyribose DNA Guanine (G). Hydrogen Nucleic acid Nucleotide Phosphate Thymine (T).

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Molecular evolution of rDNA in sturgeons: features and mechanisms

Molecular evolution of rDNA in sturgeons: features and mechanisms. Constantine V. Rozhkovan Galina N. Chelomina. Diagram of the rDNA array of eukaryotes.

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Stingrays

Stingrays. Made by Christopher Bough 7 th Grader. What are Stingrays.

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