'Phosphorylation' diaporamas de présentation

Nucleotide Metabolism

Nucleotide Metabolism. Pathways in nucleotide metabolism. De novo and salvage pathways Nucleic acid degradation and the importance of nucleotide salvage PRPP. Biosynthetic Routes: De novo and salvage pathways.

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Chapter 11 Cell Communication

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Review: Gibbs free energy, enthalpy, entropy Work and energy storage/utilization in biological systems

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Growth Factors and Receptor Tyrosine Kinases

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Protein Degradation and Regulation Ubiquitin/Proteasome Pathway Guo Peng, Luo Tong and Yang Kong 2002.12.16

Protein Degradation and Regulation Ubiquitin/Proteasome Pathway Guo Peng, Luo Tong and Yang Kong 2002.12.16. I. Introduction. This pathway is the major non-lysosomal process responsible for the breakdown of most short and long-lived proteins in mammalian cells.

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Cell Communication

Cell Communication. Chapter 7. 7.1 Cell Communication: An Overview. Cells communicate with one another through Direct channels of communication Specific contact between cells Intercellular chemical messengers. Apoptosis. Fig. 7-1, p. 140. Intercellular Chemical Messengers.

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Genomics, Bioinformatics & Medicine http://biochem158.stanford.edu/

Genomics, Bioinformatics & Medicine http://biochem158.stanford.edu/. Gene Expression http://biochem158.stanford.edu/Gene%20Expression.html. Doug Brutlag Professor Emeritus of Biochemistry & Medicine Stanford University School of Medicine. Leveraging Genomic Information. Novel Diagnostics

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Photosynthesis

Photosynthesis. Plants making their own food. Role of Photosynthesis. Plants use it to make food Animals get their food from plants It produces oxygen which is needed in respiration to release energy It is responsible for forming fossil fuels It removes carbon dioxide from the air.

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The Dopamine Transporter (DAT) is responsible for re-uptake of dopamine from the synaptic cleft

Oligomerization of the Dopamine Transporter: cocaine-analog-induced conformational changes at a homodimer interface Jonathan A. Javitch, MD,PhD Columbia University. The Dopamine Transporter (DAT) is responsible for re-uptake of dopamine from the synaptic cleft. Amph.

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What does a cell need? Building blocks biological molecules, ions, metals, water, etc. Catalysts (enzymes) reactions h

What does a cell need? Building blocks biological molecules, ions, metals, water, etc. Catalysts (enzymes) reactions happen rapidly enough to sustain life Information nucleic acids Energy. What do we need energy for? synthesis mechanical work active transport

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ATP Powered Pumps

ATP Powered Pumps. By Adam Attebery. Introduction . General information about ATP activated pumps Four different classes of ATP activated transmembrane proteins Function and examples of each Mechanism of each. ATP Powered Pumps .

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Academic Half-Day The Chemical Basis for Neuronal Communication

Academic Half-Day The Chemical Basis for Neuronal Communication. Marie-Pierre Thibeault-Eybalin, R4 November 5 th , 2008. Introduction. 100 billion (10 11 ) neurons in the brain Up to 100,000 terminal contacts / neuron 10 16 connections between neurons / brain Connections = Synapses

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a look into Cellular Respiration

a look into Cellular Respiration. All organisms need a s ource of energy and a source of Carbon!. What is a heterotroph ?. An organism that needs to CONSUME something for food/energy. What substance is required for cellular respiration to occur?. Glucose. Where does glucose come from?.

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MAP kinase Pathways in Yeast

MAP kinase Pathways in Yeast. How are signals specified between pathways that share Common components? MAP = mitogen activated protein kinase. FGP ? Cdc42/Ste20 Ste11 Ste7 Kss1 Ste12/ Tec1. PRP Ste2/3/4/18 Cdc42/Ste20 Ste11 Ste7 Fus3 Ste12. Ste5. Two MAP kinase pathways.

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General Shape of a Smooth Muscle Cell

General Shape of a Smooth Muscle Cell. Smooth Muscle Motor Units?. Contraction Patterns in Smooth Muscles. Phasic (quick, SkMus-like) and tonic contractions. EC Coupling in Smooth Muscle. Thin and Thick Filament Arrangements in Smooth Muscle. Caldesmon. Caldesmon In Relaxed Fibers.

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FIGURE 11.1. The glucose carrier switches easily between two shapes.

FIGURE 11.1. The glucose carrier switches easily between two shapes. UNFIGURE 11.1. .

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Enzyme Regulation

Enzyme Regulation. C483 Spring 2013. Questions. 1. Which statement is false about allosteric regulation? A) It is usually the mode of regulation for the last step in reaction pathways since this step produces the final product.

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Cellular Communication

Cellular Communication. Chemical messages which elicit a response in cells serve as a form of communication between cells Found in all cells S imilar in widely different organisms (such as humans and yeast) leads one to believe that this evolved very early in the history of life

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Inhibitory and Excitatory Signals

Inhibitory and Excitatory Signals . Excitatory Potentials. Excitatory postsynaptic potential (EPSP) occurs when membrane potential goes toward threshold (becomes more depolarized). ACh and Glutamate gated ion channels are excitatory.

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DAT

PKC phosphorylates the transporter. DAG and AA both stimulate the activity of Protein Kinase C (PKC). PLA2 produces arachidonic acid. PLC produces IP3 and DAG. High intracellular pH stimulates Phospholipase A2 action. Transporter of the amphetamine and Na+ lead to an AMPH and Na+ build up.

300 views • 9 slides