'Pyruvate dehydrogenase' diaporamas de présentation

? KG + 3NADPH + NH 3 + 2ATP ---> proline + 3NADP + + 2ADP + 2P i

? KG + NADPH + NH 3 + ATP ---> glutamate + NADP + + ADP + P i. ? KG + 3NADPH + NH 3 + 2ATP ---> proline + 3NADP + + 2ADP + 2P i. Proline degradation. Proline. Pyrroline-5-carboxylate. Non-enzymatic. Glutamate semialdehyde dehydrogenase. Glutamate semialdehyde. Glutamate.

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Carbohydrate metabolism

Carbohydrate metabolism. Chapter 3 (cont.). Break-down of glucose to generate energy. - Also known as Respiration. - Comprises of these different processes depending on type of organism : I. Anaerobic Respiration II. Aerobic Respiration . Anaerobic Respiration.

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Why is Patrick Paralyzed?

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Lecture on Citric Acid cycle

Lecture on Citric Acid cycle. www.AssignmentPoint.com. Overview and brief history Pyruvate Dehydrogenase Complex (PDC) and its control Reactions of TCA cycle or CAC Amphibolic nature of TCA cycle Regulation of TCA cycle

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tca cycle

TCA CYCLE

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Citric Acid Cycle

Citric Acid Cycle. Gylcolysis. Electron Transport and Oxidative phosphorylation. TCA Cycle. The TCA Cycle. (aka Citric Acid Cycle, Krebs Cycle) Pyruvate (actually acetate) from glycolysis is degraded to CO 2 Some ATP is produced More NADH is made

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CITRIC ACID CYCLE -Pyruvate Dehydrogenase

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SURVEY OF BIOCHEMISTRY Citric Acid Cycle

SURVEY OF BIOCHEMISTRY Citric Acid Cycle. PRS. Which substrates in the TCA cycle are coupled to the production of CO 2 ? Isocitrate and alpha-ketoglutarate Citrate and alpha-ketoglutarate Oxaloacetate and citrate Succinate and malate. PRS Answer. Isocitrate and Alpha-ketoglutarate. PRS.

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Figure 11.01 The citric acid cycle in context.

Figure 11.01 The citric acid cycle in context. Figure 11.02 Structor of the E 2 core of the pyruvate dehydrogenase complex from B. stearothermophilus. Figure 11.03 Thiamine pyrophosphate (TPP). Figure 11.04 Lipoamide. Figure 11.05 Flavin adenine dinucleotide (FAD).

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Glycolysis and Citric Acid Cycle Bridged via Pyruvate Dehydrogenase

Glycolysis and Citric Acid Cycle Bridged via Pyruvate Dehydrogenase. Glycolysis are Cytosolic Enzymes While Mitochondria Complete Respiration. Pyruvate is moved from the cytosol to the mitochondrion Matrix membrane permeability is critical . Citric Acid Entry Point: Acetyl CoA.

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Enzymes

Enzymes. Introduction to enzyme structure and function, and factors involving their actions and pathways. What is an enzyme?.

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Energy production and catabolism

Energy production and catabolism. TABLE 13.1. ATP contains a base, sugar, and three phosphates. Under physiological conditions, ATP always forms a complex with Mg 2+ . Adenosine Triphosphate. Figure 13.6. Figure 13.7A.

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???? TCA

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Eric Niederhoffer SIU-SOM

A 54-year-old female presents to her family physician's office with a 2 week history of pain and numbness in her left hand. A 7-year-old boy is brought to the physician with a recent history of decreased activity.

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Fate of Pyruvate & Citric Acid Cycle

Fate of Pyruvate & Citric Acid Cycle. Introduction of Glucose Metabolism Lecture-3. Fate of pyruvate. 1- Lactate (in cytosol ) Enzyme: lactate dehyrogenase (LDH) in anaerobic glycolysis 2- Acetyl CoA in mitochondria Enzyme: pyruvate dehydrogenase

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Chapter 16.1: Production of Acetyl-CoA

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Coenzyme A

ser - protein. Coenzyme A. Pantothenate. 2-mercaptoethylamine. ADP. Acyl carrier protein. Fritz Lipmann. Noble prize for Chemistry 1953 (shared with Sir Hans Krebs). "for his discovery of co-enzyme A and its importance for intermediary metabolism". 1899-1986. Pyruvate dehydrogenase.

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Targeting Cancer Metastasis Through Inhibiting Crucial Metabolic Enzyme

Center for the Study of Biological Complexity. Targeting Cancer Metastasis Through Inhibiting Crucial Metabolic Enzyme. Lucas Rizkalla. Center for the Study of Biological Complexity. What are some limitations to current cancer therapies?. Drug resistance Toxicity to healthy cells

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Eric Niederhoffer SIU-SOM

SSB End of Unit Review. Eric Niederhoffer SIU-SOM. Submitted Questions. Which enzymes are inhibited by elevated NADH versus which steps cause elevated NADH ? Inhibited: Dehydrogenases Elevated: ADH, AlDH Specific inhibitory/activating substrate interactions with PFK1, PFK2

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Carbon Tracing from Glucose

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