'Quantitative proteomics' diaporamas de présentation

Quantitative proteomics - PowerPoint PPT Presentation

Quantitative proteomics

Quantitative proteomics

Quantitative proteomics. Peking Union Medical College Chinese Academy of Medical Sciences Wei Sun sunwei1018@sina.com. Content. 1.Introduction 2. MS-based methods 3. Gel-based methods. Petterson SD, et al. Nat Genetics, 2003, 33, 311-23.

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1.75k views • 71 slides
Proteomics and mass spectrometry

Proteomics and mass spectrometry

Proteomics and mass spectrometry. Manimalha Balasubramani. Outline. Mass spectrometers Protein identification Quantitative proteomics Protein-protein interactions. 1258.5603. 100. 1303.7007. 6.3E+4. 90. 80. 70. 60. 878.4913. % Intensity. 1031.5374. 983.4860. 50.

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1.2k views • 51 slides
Phosphoproteomics and Cancer

Phosphoproteomics and Cancer

Phosphoproteomics and Cancer. Scott A. Gerber, PhD Departments of Genetics and Biochemistry Norris Cotton Cancer Center Geisel School of Medicine at Dartmouth. Kinases, cell division and cancer. CDK1 Plk1 Aurora A. CDK1 Plk1 Aurora A. CDK1 Plk1 Aurora A/B. PP1. Prophase.

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608 views • 18 slides
MS of Intact Complexes and Hybrid Technologies

MS of Intact Complexes and Hybrid Technologies

MS of Intact Complexes and Hybrid Technologies. Elise Cai Bi/Ch132 11-27-12. Protein Complexes. Subunit composition, stoichiometry Protein-protein interactions Architectural organization Dynamic changes. Native MS. MS of whole protein assemblies Examine large, heterogeneous complexes

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264 views • 17 slides
Protein Quantification Service

Protein Quantification Service

As we all know, dynamic changes of proteome abundance in cells have important effects on various life processes.

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79 views • 4 slides
Protein Quantification

Protein Quantification

In order to assess the biological function of proteins and their modifications for understanding signaling mechanisms within cells as well as specific biomarkers to disease, it is important to study the change of proteome under different experimental conditions. The emerging technology of mass spectrometry-based quantitative proteomics provides a powerful tool to quantitatively and systematically assess quantitative differences in protein profiles of distinct samples and is increasingly becoming a significant component of biomedical and clinical research.

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37 views • 2 slides

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