Rko cells - PowerPoint PPT Presentation

Lopez de Silanes et al. Suppl-Fig.1

t 1/2 (Cispl)&gt;8 h. 100. t 1/2 (Untr)&gt;8 h. 50. t 1/2 (Cispl)=3.27 h. Percent mRNA remaining (Normalized to 18S rRNA). t 1/2 (Untr)=2.13 h. GAPDH in HuR siRNA cells. DNMT3b in HuR siRNA cells. 10. 0. 0. 2. 4. 6. 0. 2. 4. 6. Time in Actinomycin D (h).

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pcDNA5 PGK pcDNA5 PGK

MoL #33472. shPGK shPGK + dox 0.05ng/ml shPGK + dox 5ng/ml shPGK shPGK + dox 0.05ng/ml shPGK + dox 5ng/ml. Sh-control Sh-control + dox 5ng/ml Sh-control Sh-control + dox 5ng/ml. shHIF-1 α shHIF-1 α + dox 5ng/ml shHIF-1 α shHIF-1 α + dox 5ng/ml. Supplemental Fig.5. pcDNA5 PGK

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Supplemental Fig.7

MoL #33472. Supplemental Fig.7. A B. C C.

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LoVo

DAPI. HDAC2. MERGED. DAPI. HDAC1. MERGED. b. a. HCT116. HCT116. LoVo. LoVo. Co115. Co115. RKO empty vector. RKO empty vector. RKO HDAC2 transfection. RKO HDAC2 transfection.

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Supplemental Fig.6

MoL #33472. Supplemental Fig.6. A B. C D.

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