'Taxol' diaporamas de présentation

Alcohols

Alcohols. Biological Activity Nomenclature Preparation Reactions. Some Alcohols. Alcohols are Found in Many Natural Products. Paralytic Shellfish Poisoning. Ethanol: the Beverage. Excess NADH can cause Metabolic Problems. Methanol: Not a Beverage. Synergistic and Metabolic Effects.

821 views • 63 slides

Combined approaches to Drug Discovery

Combined approaches to Drug Discovery. In lecture, we will be focusing at different points on natural products, receptor-based design, and pharmacophore-based design of drugs In reality, drug development may combine these elements into a synthetic approach

845 views • 39 slides

Organic Synthesis

Molecular things you have. Organic Synthesis. chemists. ?. Molecular things you want. Nam Le. Molecular things you have. Molecular things you want. Synthesis Requires Two Things. 1. a library of reactions. 2. a strategy or plan for combining known reactions to reach

526 views • 31 slides

Secondary Products

578 views • 24 slides

? ? ? ? ? ? ? ? ?????? Taxol

? ? ? ? ? ? ? ? ?????? Taxol. ??? : ??? ??? : ??? ???? :91.1.11 1300~1400. ??. ???? ?????? ?? Taxol ??? ?? Taxol ????? ?? Taxol ???? ?? Paclitaxel(Taxol) ? Docetaxel(Taxotere) ??? ?????? ???? ??????. ????. ? ?? ? ????????????????? ?????????? ? ?????????????????????

1.42k views • 23 slides

FBW7/CDC4 and Endometrial Cancer

FBW7/CDC4 and Endometrial Cancer. Michael Mastropole. Overview. FBW7/CDC4 is a family of genes Tumor suppressor Directly binds to cyclin E Mutated in about 16% of endometrial cancers. Ubiquitylation. http://upload.wikimedia.org/wikipedia/commons/7/7f/Ubiquitylation.png.

246 views • 12 slides

D9 Drug design

D9 Drug design. Daniel Brown. D9.1 Discuss the use of a compound library in drug design. Traditionally, a large collection of related compounds are synthesized individually and evaluated for biological properties. However t his is time consuming and expensive.

241 views • 11 slides

12 hr. 24 hr. Taxol:. 0 hr. 24 hr + PurvA. Time (hrs): -24 0 12-15 24-27. Cell Cycle Phase: Asyn. G1/S Mitosis. Thymidine block. Thymidine Wash-out; +/-Taxol;

196 views • 8 slides

Stat 13 Lecture 24 regression(continued)

Stat 13 Lecture 24 regression(continued). Application in drug discovery ( http://dtp.nci.nih.gov ) COMPARE Antitubulin Taxol (EX=-7.9; SD=.78) vinblastine sulfate (EY=-8.1; SD=.81) ; correlation =0.799 Prediction

209 views • 5 slides