'Total lod score' diaporamas de présentation

Study Design for Linkage, Association and TDT Studies

Study Design for Linkage, Association and TDT Studies. ??? Ming-Wei Lin, PhD ???????????? ????????????. Collins FS. (1992) Nature genetics 1:3-6. Collins FS. (1992) Nature genetics 1:3-6. Linkage Mapping for Disease Genes. Linkage analysis (Lod score method) Allele-sharing methods.

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Mapping genes with LOD score method

Mapping genes with LOD score method. LOD score method. Aim: Determine ? , the recombinant fraction (fraction of gametes that are recombinant), using data from relatively small families. Reminder: ? vary from 0 (2 genes completely linked) to 0.5 (2 genes are unlinked).

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Linkage analysis - genehunting

293 views • 14 slides