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OUTLINE 17 VII. Mutation A. Point Mutations 1. Substitution 2. Insertion 3. Deletion

OUTLINE 17 VII. Mutation A. Point Mutations 1. Substitution 2. Insertion 3. Deletion B. Causes of Mutation C. Consequences of Mutation 1. Beneficial 2. Neutral 3. Deleterious 4. Lethal 5. Heritable D. Frequency of Mutations E. Examples F. Chromosomal abnormalities

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OUTLINE 17 VII. Mutation A. Point Mutations 1. Substitution 2. Insertion 3. Deletion

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  1. OUTLINE 17 VII. Mutation A. Point Mutations 1. Substitution 2. Insertion 3. Deletion B. Causes of Mutation C. Consequences of Mutation 1. Beneficial 2. Neutral 3. Deleterious 4. Lethal 5. Heritable D. Frequency of Mutations E. Examples F. Chromosomal abnormalities 1. Chromosome breakage 2. Aneuploidy and non-disjunction

  2. Predator absent Predator present Phenotypic plasticity in Daphnia

  3. Crayfish predator Sunfish predator Snail prey

  4. A full sib raised with crayfish A snail raised with fish Phenotypic plasticity in shell morphology in Physis

  5. Phenotypic plasticity in leaf morphology in Viola

  6. The genetic code

  7. Consequences of a frame shift mutation: THE BIG CAT ATE THE RED EGG THB IGC ATA TET HER EDE GG. …

  8. PKU disease - an autosomal recessive trait X

  9. Albinism

  10. Sickle cell Normal red blood cell Sickle cell anemia: an autosomal co-dominant

  11. Fig. 15.11: Non-disjunction leading to aneuploid gametes

  12. Turner’s syndrome XO

  13. Klinefelter’s syndrome XXY

  14. XYY Male

  15. Cri du chat

  16. = male = female Fig 14.14 Use of pedigree analysis ff Ff ff Ff ff Ff ff = attached ff Ff OR FF Attached earlobe Free earlobe

  17. Sex chromatin: Barr body

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