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Incomplete Repressors in Phages

Incomplete Repressors in Phages. Mandi Feinberg BNFO 301 Spring 2013. Phages. Bacteria. Phages. Mycobacteria Phages. Limitations.

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Incomplete Repressors in Phages

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  1. Incomplete Repressors in Phages Mandi Feinberg BNFO 301 Spring 2013

  2. Phages Bacteria

  3. Phages

  4. Mycobacteria Phages

  5. Limitations • When I find motifs that may be incomplete– won’t know what phage it belongs to since I used randomization and MEME only gives sequence numbers so its impossible match it back • Have to go through in sections and label them and find motifs in order • Limited to about 20 before times out • No matter how fix it, it will be a long, complicated process

  6. Works Cited • http://www.sciencedirect.com/science/article/pii/S1097276512009434 • Broussard, Gregory W., Lauren M. Oldfield, Valerie M. Villanueva, Bryce L. Lunt, Emilee E. Shine, and Graham F. Hatfull. "Integration-Dependent Bacteriophage Immunity Provides Insights into the Evolution of Genetic Switches." Molecular Cell 49 (2013): 237-48. • http://biobike.phantome.org/ajax/vpl.html?PKG=FEINBERGMA39619 • Intro to BNFO 301 Exam 2 • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC94198/ • The Genetic Switch Regulating Activity of Early Promoters of the Temperate Lactococcal Bacteriophage TP901-1 • Peter Lynge Madsen, Annette H. Johansen, Karin Hammer, Lone Brøndsted • J Bacteriol. 1999 December; 181(24): 7430–7438.

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