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Innovative Microscale Chemistry Experiments for Science Education

Explore MicroQuim 2000, a project from the University of Amsterdam's Faculty of Science focusing on microscale chemistry experiments. Discover low-cost heating devices, column chromatography, indigo synthesis, and more. Replace macroscale experiments with quick, curriculum-fitting activities that open new perspectives.

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Innovative Microscale Chemistry Experiments for Science Education

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  1. Erik JolingSome examples from the project ‘Microscale experiments’ UNIVERSITEIT VAN AMSTERDAM Faculty of Science

  2. Prime Directive of Microscale Chemistry Thou shalt not demonstrate MicroQuim 2000

  3. Glassware MicroQuim 2000

  4. Low-cost heating device MicroQuim 2000

  5. Chlorophyll from green leaves • methanol • green leaves MicroQuim 2000

  6. Experiments must… …be performed during a forty-five minute period …fit into the curriculum …replace the macroscale experiments in the textbook …open new perspectives MicroQuim 2000

  7. Column chromatography • aluminium oxide • mixture of potassium permanganate and potassium dichromate • 0.5M nitric acid • 1M sulfuric acid MicroQuim 2000

  8. Synthesis of indigo • 0.1 g 2-nitrobenzaldehyde • 0.3 ml acetone • 0.4 ml water • 2 ml 1M sodium hydroxide • 2 ml ethanol • 0.1 g sodium dithionite MicroQuim 2000

  9. Indigo STS-topic: • age-old natural dye • first synthetic dye • production by Hoechst and the decline of the Indian indigo culture MicroQuim 2000

  10. Sublimation of benzoic acid • benzoic acid • activated carbon • crunched ice MicroQuim 2000

  11. Esterificationacetic acid + 1-butanol = 1-butyl acetate + water One reaction, three experiments: • use of a catalyst • determination of equilibrium constant • upset the equilibrium MicroQuim 2000

  12. Contact me micro@chem.uva.nl www.chem.uva.nl/chemeduc/microschaal …/MicroQuim2000 MicroQuim 2000

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