1 / 15

Side chain oxidation

Side chain oxidation. Lab 2 . Side chain. It’s the aliphatic portion of the alkylbenzene . . Benzylic Radicals and Cations. Terms you should know : Free Radicals Benzylic radical Benzylic hydrogen atom Benzylic cation. Free Radicals.

stacie
Télécharger la présentation

Side chain oxidation

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Side chain oxidation Lab 2

  2. Side chain It’s the aliphatic portion of the alkylbenzene.

  3. Benzylic Radicals and Cations • Terms you should know : • Free Radicals • Benzylicradical • Benzylic hydrogen atom • Benzyliccation

  4. Free Radicals • An atom or group of atoms that has at least one unpaired electron ,so: • Unstable • Highly reactive

  5. Benzylic radical • Is the general name applies to all radicals that have unpaired electron on the carbon atom attached directly to the benzene ring.

  6. Benzylic hydrogen atoms • Is the hydrogen atom of the carbon atom that directly attached to the benzene ring.

  7. Benzyliccation: • Is the departure of a leaving group (LG) from a benzylic position.

  8. Halogenation of the side chain vs ring halogention

  9. Bromination Chlorination

  10. Benzylichalogenation Chain Initiation Step 1 Chain propagation Step 2

  11. Benzylichalogenation Step 3 Chain Termination Step 4

  12. Oxidation of the side chain • The oxidation can be carried out by the action of hot alkaline potassium permanganate.

  13. Oxidation of the side chain • Oxidation of the side- chain take place initially at the benzylic carbon; any alkylbenzenes with alkyl group longer than methyl are ultimately degraded to benzoic acids:

  14. Oxidation of the side chain • Reaction:

  15. Thank you

More Related