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Quiz. Adverse Drug Reactions. Fill in the blanks. Adverse drug reactions are any noxious, __________, and __________ effect of a drug that occurs at doses used for prevention, diagnosis, or treatment. Type A reactions are _____________ reactions.
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Quiz Adverse Drug Reactions
Fill in the blanks • Adverse drug reactions are any noxious, __________, and __________ effect of a drug that occurs at doses used for prevention, diagnosis, or treatment. • Type A reactions are _____________ reactions. • Drug allergies are examples of _________ reactions.
Fill in the blanks • A ______________ is an essential component in the evaluation of patients with suspected drug allergies. • Incidence of aspirin/NSAID hypersensitivity is higher for __________ than the general population.
Fill in the blanks • Pseudo-allergic reactions from NSAIDs are due to _______________________. • ____________ manifestations are the common clinical manifestations of immunologically mediated ADR’s.
Enumeration • 8 – 9. Give two methods of managing ADR’s. • 10 – 12. Give three ways of preventing ADR’s.
Fill in the blanks • Adverse drug reactions are any noxious, undesired, and unintended effect of a drug that occurs at doses used for prevention, diagnosis, or treatment. • Type A reactions are predictable reactions. • Drug allergies are examples of type B reactions.
Fill in the blanks • A thorough history is an essential component in the evaluation of patients with suspected drug allergies. • Incidence of aspirin/NSAID hypersensitivity is higher for asthmatics than the general population.
Fill in the blanks • Pseudo-allergic reactions from NSAIDs are due to inhibition of COX 1. • Cutaneous manifestations are the common clinical manifestations of immunologically mediated ADR’s.
Enumeration • 8-9. Give two methods of managing ADR’s. • Stop the suspected drug/s • Substitute with an alternative non-cross-reacting agent, preferably from a different therapeutic class • Desensitization • Induction of drug tolerance or graded challenge procedures
Enumeration • 10 – 12. Give three ways of preventing ADR’s. • Judicious use of drugs • Patient education • Medical alert cards/bracelets • Pharmacovigilance or ADR reporting • Electronic medical records
Thank you for listening! (Score over 10)