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Exploring Cell Structural Engineering: Determining Centrosome Location and Measuring Forces in Macromolecular Beams

Dive into the world of cell structural engineering by understanding how centrosome location is determined and measuring forces exerted by microtubule polymerization. Learn about beam bending and the methods to measure forces in this intricate field.

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Exploring Cell Structural Engineering: Determining Centrosome Location and Measuring Forces in Macromolecular Beams

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Presentation Transcript

  1. Structural Engineering of Cells: Macromolecular Beams

  2. How is the centrosome location determined? Alberts, et al., EBC Alberts, et al., MBoC

  3. Putting structure to work... • How would you measure the forces exerted by MT polymerization? • How do we measure any force? Paul Wiggins

  4. Beam Bending

  5. Beam Bending Assume neutral axis unstretched

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