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Vascular effects : indapamide SR vs hydrochlorothiazide

Vascular effects : indapamide SR vs hydrochlorothiazide. A O. Ciobanu, R. Dulgheru, S. Magda, Eur J Echocardiography Abstracts Supplement, December 2011. What are the effects of. HCTZ + ACE inhibitor. Indapamide SR + ACE inhibitor. on ventriculoarterial coupling :

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Vascular effects : indapamide SR vs hydrochlorothiazide

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  1. Vasculareffects: indapamide SRvs hydrochlorothiazide A O. Ciobanu, R. Dulgheru, S. Magda, Eur J Echocardiography Abstracts Supplement, December 2011

  2. What are the effects of HCTZ + ACE inhibitor Indapamide SR+ ACE inhibitor on ventriculoarterialcoupling: Endothelial and arterialfunction Leftventricularfunction Biomarkers

  3. PROBE Design 6 months Quinalapril + indapamide SR 56 Diabetic hypertensive patients with normal EF • Doppler • Echocardiography • Endothelial FMD • Biomarkers Quinalapril + HCTZ

  4. Improvement in longitudinal LV function with indapamide SR, but not HCTZ DOPPLER +31% P<0.05 cm/s Indapamide SR effects +14% P<0.05 +13% P<0.05 +7% P<0.05 Baseline 6 months No change in EF and radial systolicvelocity

  5. with indapamide SR, but not HCTZ: Improvement in endothelial and arterialfunction FMD increased by 19% Microalbuminuria decreased by 30% Arterial function: pulse wave velocity decreased by 4%

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