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Keratometric Changes in Noninflammatory Corneal Ectasic Diseases After Intraocular Pressure Reduction

Keratometric Changes in Noninflammatory Corneal Ectasic Diseases After Intraocular Pressure Reduction. Authors has no financial interest. Renata T Kashiwabuchi, Camila Gadelha, Wilson de Freitas, Carlos Arce, Mauro Campos

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Keratometric Changes in Noninflammatory Corneal Ectasic Diseases After Intraocular Pressure Reduction

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  1. Keratometric Changes in Noninflammatory Corneal Ectasic Diseases After Intraocular Pressure Reduction Authors has no financial interest. Renata T Kashiwabuchi, Camila Gadelha, Wilson de Freitas, Carlos Arce, Mauro Campos Federal University of Sao Paulo, Paulista School of Medicine – Sao Paulo, Brasil

  2. Purpose: To assess possible keratometric changes after intra-ocular pressure reduction and describe any change observed.

  3. Methods • Ten patients: 9 bilateral keratoconus and 1 corneal ectasia after refractive procedure. • All patients were submitted to the follow exams before and after intra-ocular pressure reduction: • Corneal Analysis System EyeSy (EyeSys Laboratories Incorporation, Houston, Texas, USA), • Pentacam (Oculus, Wetzlar, Germany), • Corneo-Gage Plus (Sonogage, Cleveland, OH), • Galilei (Zymer, SMT Swiss Microtechnology AG, Port, Switzerland) • Ocular Respose Analyser (ORA; Reichert Ophthalmic Instruments, Depew, NY), • Intra-ocular pressure was measured by Goldman applanation tonometer in 90 and 180 axes by examiner 1 as well as all exams.

  4. Methods • For each patient one eye was assigned randomly to receive hypotensive drugs. Instructions about the drops were given to the patients by examiner 2. • Examiner 1 has no access to details of random process.

  5. Results (table) • Significant differences were observed in the follow data (hypotensive group): • PIO (Goldman) = 5.45 ± 2.3 mmHg (p=0.00), • Pentacan • Anterior Chamber Depth= 3.5 ± 0.3 µm (p = 0.04) • Anterior Chamber Volume= 218 ± 42.95 mm3 (p= 0.004), • ORA data: • IOPcc= 8.1 ± 3.1 mmHg (p= 0.00), • IOPg= 4.75 ± 2.1mmHg (p= 0.00) • CRF= 6.0 ± 0.4 (p= 0.01).

  6. Results (abbreviation) • IOP (Goldman)= Intra ocular pressure assessed by Goldman Tonometry • Km =mean simulated K power • P= Pentacan • Km post = posterior corneal power • ACV = Anterior Chamber Volume • ACD = Anterior Chamber Depth • G = Galilei • IOPcc = Corneal Compensated Intra Ocular Pressure • IOPg = Goldman Compensated Intra Ocular Pressure • CRF = Corneal Resistance Factor • CH = Corneal Histeresis

  7. Data from hypotensive group

  8. Conclusion: Even though a significant intra-ocular pressure reduction no keratometry changes were observed in no device used.

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