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Probability of OS (%)

Stupp Trial: Improved survival with TMZ Chemotherapy. 100. 90. 80. RT + TMZ. 70. RT. 60. Probability of OS (%). 50. 40. 30. 20. 10. 0. 6. 12. 18. 24. 30. 36. 42. Months. No. at Risk. RT 286 240 144 59 23 2 0 RT+TMZ 257 216 174 109 57 27 4

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Probability of OS (%)

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  1. Stupp Trial: Improved survival with TMZ Chemotherapy 100 90 80 RT + TMZ 70 RT 60 Probability of OS (%) 50 40 30 20 10 0 6 12 18 24 30 36 42 Months No. at Risk RT 286 240 144 59 23 2 0 RT+TMZ 257 216 174 109 57 27 4 HR 0.63 (95% Cl, 0.52 to 0.75; p<0.001) Adapted from Scrive et al. ASTRO 2007

  2. Long-term Survival Adapted from Mirimanoff et al. ASTRO 2007.

  3. MGMT Gene Status: Survival at Four Years Adapted from Mirimanoff et al. ASTRO 2007.

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