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Understanding Animal Testing in Toxicology: Principles and Practices in New Zealand

This content explores the principles of animal testing in New Zealand, focusing on the 3Rs: Replacement, Reduction, and Refinement. It discusses the scale of animal use in research, teaching, and testing, highlighting that 301,964 animals were used in 2012, predominantly cattle and mice. The ethical considerations under the Animal Welfare Act 1999 are outlined, emphasizing the need for ethics approval for research activities. The aim is to foster informed discussion on animal testing, relevant laws, and alternatives.

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Understanding Animal Testing in Toxicology: Principles and Practices in New Zealand

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Presentation Transcript

  1. Animal testing in toxicology

  2. Learning objectives • Understand the principles that underpin animal use in New Zealand • Be able to define and discuss the principle of the 3Rs • Be able to articulate a viewpoint on animal testing and be able to relate it to specific examples and the New Zealand law.

  3. Animal use in NZ • 301,964 animals were used in NZ in 2012 for research, teaching and testing • 41.3% of these were cattle • 18.5% were mice • Over 10,000 mice were involved in experiments categorised as high or very high impact. • 12.8% were sheep

  4. Most rodents were euthanised

  5. What is your reaction to these numbers?

  6. Control of animal use • Regulated under the Animal Welfare Act 1999 (part 6) • Obligation to care for animals • Definition of animal • Mammals, birds, reptiles, amphibians, fish, crabs, crayfish, squid and octopus • Must have animal ethics approval to carry out research, teaching or testing

  7. The 3Rs • Replacement • Replacing animal with non-animal alternatives • Reduction • Using as few animals as necessary • Refinement • Pain or suffering must be reduced as much as possible

  8. Some major players

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