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The study explores how miR-34/449 deficiency affects ciliogenesis in respiratory multiciliated cells, leading to defects. Research by Song et al. in Nature highlights the crucial role of miR-34/449 in maintaining proper ciliary function in MCCs.
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miR-34/449 deficiency causes ciliogenesis defects in respiratory MCCs. R Song et al. Nature 510, 115-120 (2014) doi:10.1038/nature13413