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Teach Evolution Learn Science

MOLECULAR EVOLUTION MB437 and ADVANCES IN MOLECULAR EVOLUTION MB537SYLLABUSLecture 1 8/28/07 Comments. Organization

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Teach Evolution Learn Science

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    6. Possible Ways Bioinformational Molecules Arose

    8. Proteins: The First Bioinformational Molecules? Even small, randomly synthesized peptides, exhibit function. Must invent translation.

    9. Nucleic Acids: The first bioinformational molecules? Ribozymes exist: catalysis sans proteins Elongation Ligation and autocatalytic replication cleavage Much harder to make nucleotides under prebiotic conditions. No arbitrary ssRNA or DNA has been sythesized yet by any method. Need to invent genetic code, the initial step in translation.

    11. Why is it hypothesized that RNA preceded DNA as the genetic information? Deoxyribonucleotides are synthesized from ribose intermediates.

    17. What are the Questions?

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