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miR-9

Supplementary Fig. S1. 23.4. miR-503. 22.9. 13.4. 12.2. 10. 8. 6. Relative expression (/ C20 normal liver). 4. 2. 1. 0. -. -. -. -. -. +. +. +. +. +. +. +. +. +. +. +. +. +. +. +. +. +. +. +. *36.8% (7/19). Methylation. 71.2. miR-9. 14.7. 11.8. 10.3.

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miR-9

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  1. Supplementary Fig. S1 23.4 miR-503 22.9 13.4 12.2 10 8 6 Relative expression (/ C20 normal liver) 4 2 1 0 - - - - - + + + + + + + + + + + + + + + + + + + *36.8% (7/19) Methylation 71.2 miR-9 14.7 11.8 10.3 10 8 Relative expression (/ C20 normal liver) 6 4 2 1 0 Methylation - - - - - + + + + + + + - + + + + + + + + + + + miR-9-1 *33.3% (6/18) - - - - - + + + + + - - - + + + - + + + + - - + miR-9-3 *46.2% (6/13) 135 miR-129 109 25.2 10 8 Relative expression (/ C20 normal liver) 6 4 2 1 0 *35.3% (6/17) - - - - - + + + + + + + - + + + + + + + + + - + Methylation 1.4 miR-596 1.2 1.0 0.8 Relative expression (/ C20 normal liver) 0.6 0.4 0.2 0 *75.0% (12/16) + - - - - - + + + + + + + - + + + - + + + + - + Methylation 556 394 miR-137 285 229 55.8 11 38.5 10 8 Relative expression (/ C20 normal liver) 6 4 2 1 0 - - - - - + + + - + - - + + + + + + + + + + - + *26.7% (4/15) Methylation miR-196b 744 343 388 45.9 336 186 56.9 35.1 92 23.2 52 88.7 77.4 27.7 10 8 Relative expression (/ C20 normal liver) 6 4 2 1 0 - - - - - - + + + + + + + - - - + + + + + + + + *0% (0/15) Methylation 38.8 miR-149 21.6 14 12 10 Relative expression (/ C20 normal liver) 8 6 4 2 1 0 - - - - - - - - - - *7.7% (1/13) + + + + + + + + + + + + + + Methylation Li7 C20 C40 HLF HLE cHc4 Huh7 huH-1 JHH-1 JHH-2 JHH-4 JHH-5 JHH-6 JHH-7 HuH-6 LC08N LC07N LC11N Hep 3B Hep G2 sK-Hep-1 PLC/PRF/5 Hep-KANO Hep-TABATA HCC cell lines

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