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Effects of Exercise Training and Simvastatin on Citrate Synthase Activity: A Study by Mikus et al.

This study explores the impact of exercise training, both with and without simvastatin, on citrate synthase activity in individuals. Utilizing a controlled environment, Mikus et al. assess changes in mitochondrial function before and after an exercise regimen. The findings contribute to the understanding of how statin therapy may influence the physiological adaptations to regular physical activity, potentially affecting metabolic health. Published in the Journal of the American College of Cardiology (JACC) in 2013, this research aids in optimizing exercise prescriptions for patients on statins.

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Effects of Exercise Training and Simvastatin on Citrate Synthase Activity: A Study by Mikus et al.

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  1. Ex: exercise training St+Ex: exercise training + simvastatine Peakoxygenconsumptionbefore and afterexercise training withor without simvastatin Mikuset al. JACC 2013

  2. Ex: exercise training St+Ex: exercise training + simvastatine Citratesynthaseactivitybeforeand afterexercise training withor without simvastatin Mikuset al. JACC 2013

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