1 / 1

Effects of HGF Treatment on Phospho-ERK1/2 and MEK1/2 Activation in Huh7 Cells

This study investigates the impact of Hepatocyte Growth Factor (HGF) on the activation of ERK1/2 and MEK1/2 pathways in Huh7 cells. Using phospho-specific assays, we measured the percentage of control for Phospho-ERK1/2 and Phospho-MEK1/2 at various time points (0.15, 30, 60, 120 minutes) following HGF treatment. Additionally, Ras-GTP activation was also assessed under the same conditions. Results demonstrate a significant temporal response of these signaling pathways to HGF stimulation, highlighting their role in cellular signaling.

velika
Télécharger la présentation

Effects of HGF Treatment on Phospho-ERK1/2 and MEK1/2 Activation in Huh7 Cells

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. PLC/PRF/5 A Phospho-ERK1/2 (% of control) HGF(min) B C Phospho-MEK1/2 (% of control) 0 15 30 60 120 0 15 30 60 120 Ras-GTP (% of control) HGF(min) HGF(min) 0 15 30 60 120 Huh7 D E Phospho-ERK1/2 (% of control) Phospho-MEK1/2 (% of control) F HGF(min) 0 15 30 60 120 HGF(min) 0 15 30 60 120 Ras-GTP (% of control) HGF(min) 0 15 30 60 120 Supplementary Fig. 2

More Related