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HARUAN SPRAY FOR BURN AND WOUND

HARUAN SPRAY FOR BURN AND WOUND. Prof. Saringat bin Bai @ Baie School of Pharmaceutical Sciences Universiti Sains Malaysia Minden 11800 Penang, Malaysia. BACKGROUND. Haruan fish contains a lot of amino acids and fatty acids  important to improve wound healing process.

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HARUAN SPRAY FOR BURN AND WOUND

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  1. HARUAN SPRAY FOR BURN AND WOUND Prof. Saringat bin Bai @ Baie School of Pharmaceutical Sciences Universiti Sains Malaysia Minden 11800 Penang, Malaysia

  2. BACKGROUND Haruan fish contains a lot of amino acids and fatty acids  important to improve wound healing process

  3. At this moment , there are two types of Haruan preparation in the market to improve wound healing.

  4. PROBLEM STATEMENT • Wound care films in the market: - have limited size and singly packed  can’t cover different sizes of wound - easily contaminated - difficult to use at certain part of body • Majority of dressings for wound such as: • plasters • bandages cause pain during dressing • Dressing pads and removal process traumatic dressing

  5. SOLUTION Haruan Spray combination between a comfortable dressing for dermal wound and to provide an adequate nutrition to the wound site

  6. NOVELTY AND USEFULNESS • Can cover any size of wound • Ease of application and removal (water washable) • Can protect the wound • Can heal the wound faster • Can replace skin graft • Product remain sterile

  7. COMPETING PRODUCT • In spray dressing form: • OpSite • Nobecutane • In film dressing form: • Tegaderm • Omiderm • Bioclusive • Dermafilm • Etc.

  8. COMMERCIALIZATION POTENTIAL • Have an agreement with Major Interest Sdn.Bhd. to manufacture and marketing the product • Market target: can be distributed to all over the world

  9. RESEARCH FUND • RU Grant of USM • 1 in 2007 : Formulation • 2 in 2009 : Wound healing test and Stability study • TechnoFund • Innofund

  10. IMPACT OF THE PRODUCT • Increase human’s health for better quality of life • Reduce the cost for patient’s ward at hospital after surgery • As an alternative for diabetic wound treatment

  11. ACADEMIC RECOGNITION • Poster and oral presentation: 9 • As invited speaker: 1 • Published Journal: 3

  12. Image at 0h Image at 2.5h Image at 5h Image at 24h Effect of haruan aqueous extract in migration of mouse fibroblast cells

  13. Image at 0h Image at 2.5h Image at 24h Image at 5 h Effect of haruan aqueous extract in migration of human foreskin fibroblast cells

  14. Irritation study of Haruan Spray in abraded and non abraded skin

  15. Day 0 Day 6 Day 3 Day 9 Day 12 Pictures of incision wound healing at day 0, 3, 6, 9, and 12

  16. Untreated Blank P1 P2 Day 3 Day 6 Day 15 Day 21 Photographs of burn wound at day 3, 6, 15 and 21 for control group (untreated), treated with blank, P1 (treated with haruan), P2 (treated with haruan+fusidic acid)

  17. A B D C Photographs of histology study of burn wound treated with (A) blank, (B) haruan, (C) haruan+ fusidic acid, (D) untreated on day 7 (magnification 100x)

  18. A B C D Photographs of histology study of burn wound treated with (A) blank, (B) haruan, (C) haruan+ fusidic acid, (D) untreated on day 14 (magnification 100x)

  19. 55 year old diabetic women got infected hand, operated and treated with CSKIN FIX cured after one month.

  20. 50 year old male diabetic patient, injured his leg and had gangrene to one of his finger, operated and treated with CSKINFIX , cure after one month. (1st Photo, two weeks in hospital, no improvement, 3rd Photo after one month treatment)

  21. Won Silver Medal In 39th Geneva International Invention,6-9 April 2011

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