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What is Anesthesia

Topics to Cover This Lecture. What is anesthesia"History and mechanism of anesthesiaUptake and distribution of inhaled anestheticsCNS effects of anesthesiaMinimal alveolar concentration (MAC)Properties of inhaled anestheticsSystem effects of inhaled anestheticsDelivery systems for inhaled an

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What is Anesthesia

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    1. What is Anesthesia? Franklin Scamman, MD

    2. Topics to Cover This Lecture What is anesthesia History and mechanism of anesthesia Uptake and distribution of inhaled anesthetics CNS effects of anesthesia Minimal alveolar concentration (MAC) Properties of inhaled anesthetics System effects of inhaled anesthetics Delivery systems for inhaled anesthetics

    3. Anesthesia Insensitivity to pain May be from local or general agents Term introduced by Oliver Wendell Holmes in 1847 in response to work by WTG Morton using ether

    4. History of Anesthesia Greeks and Romans: aware of opium and derivatives; oral ethanol Japan: 1820s, mandrake causing cholinergic crisis and unconsciousness TWG Morton, MGH, October 16, 1846 using diethyl ether However, Crawford Long in 1849 described his use of it in 1842

    5. MGH Ether Dome 1846

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