Supplementary Table 1 Patient 1 2 3 4 5 6 7 8 9 10 11 Age (y) 44 36 34 40 26 36 35 48 33 48 35 Sex1 M M M M F M M F M M M Disease duration (y) 6 11 4 11 8 7 15 14 8 17 5 Disease classification2 A2 L1 B3p A2 L1 B3p A2 L3 B3 A2 L3 B3p A2 L1 B3 A2 L3 B3p A2 L3 B3p A2 L3 B3p A2 L3 B3p A2 L1 B3p A2 L3 B3p Medications3 5ASA, 6MP, PSL 5ASA, 6MP, EN 5ASA, 6MP 5ASA, 6MP 5ASA, 6MP, EN 5ASA, 6MP 5ASA, 6MP, EN 5ASA, PSL 5ASA, 6MP 5ASA, 6MP 5ASA Smoking4 N Y N Y N N N N N N Y Previous surgeries5 S, IF, S+IF S+IF, S, S, S+EF, S+EF+A EF+A, EF+A, EF S, S+IF S+A, S+IF, S+IF S+EF+A, S, S+A, S+EF+A S, S+A, S+EF, S+A S, S+A S+A, S, S, S+EF, S+EF+A S+A, S+A, S, S+A S, S+A Most recent surgical procedure partial ileal resection partial ileal resection ileocolectomy ileocolectomy partial ileal resection ileocolectomy ileocolectomy ileocolectomy Ileocolectomy/ileostomy6 Ileocolectomy/ileostomy6 ileocolectomy Outcome Remission for 39 m Resurgery at 8 m Remission fro 48 m Remission for 63 m Remission for 33 m Remission for 39 m Recurrence 16 m IR7 at 4 m Remission for 44 m Recurrence at 20 m drop out at 6 m Colonscopy at 24 m8 SBFT no lesion i2 i0 SBFT no lesion i0 i2 Drop out 1 M: male, F: female. 2 Montreal classification. 3 5ASA: 5-aminosalicylate, 6MP: 6-mercaptopurine, PSL: prednisolone, EN: enteral nutrition. 4 Y: yes, N: no. 5 S: stricture, IF: internal fistula, EF: enterocutaneous fistula, A: abscess. The most recent reasons are indicated in bold. 6 The patients subsequently had ileostomy take down. 7 IR: infusion reaction. 8 Patients who underwent colonoscopy were assessed by the Rutgeerts’ criteria, and those that underwent small bowel follow through (SBFT) were assessed by the examining Radiologist as either having or not having any active Crohn’slesion.