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Process Platform for Rapid Screening

Innovative process platform enabling rapid screening with advantages of low flow rates, reduced reagents, suitable for various reactions, and high throughput screening capability. Application in biodiesel production and pharmaceutical production. Research conducted by Phan, Harvey, Eze, Mohd Rasdi, and Rawcliffe at Newcastle University in 2012.

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Process Platform for Rapid Screening

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  1. Process platform for rapid screening Anh N. Phan , Adam P. Harvey, Valentine Eze, Fatimah Mohd Rasdi and Martin Rawcliffe School of Chemical Engineering & Advanced Materials Newcastle University Newcastle 2nd May 2012

  2. Process platform (a) d= 5mm Oscillatory flow do/d≈ 0.5 1.5d (b) (c) 340mm (Phan et al. (2010), Chemical Engineering Journal, 159 (1-3) pp 212-219)

  3. Advantages Operate at very low net flow rates: from µl/hr to ml/hr (residence time : mins to hours) Reduce amount of reagents and waste Suitable for viscous liquid and multiphase reactions (solid-liquid, gas-liquid and solid-solid-liquid) Suitable for continuous high throughput screening & small scale pharmaceutical production

  4. Residence time distribution T= No oscillation, Ren=2.19 Applied oscillatory flow, Ren=2.55 Phan et al. (2011), Chemical Engineering and Processing: Process Intensification, 50 (3) pp 254-263

  5. Two-phase liquid reaction- Biodiesel production Residence time: 10mins Phan et al. (2012) Chemical Engineering & Technology journal , In press

  6. Two-phase liquid reaction- Biodiesel production (cont) Phan et al. (2011), Fuel Processing Technology, 92 (8) pp 1560-1567

  7. Thank you!

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