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The Effect of HIV on the Immune System

The Effect of HIV on the Immune System. Rico, Patrick, Myeong Jin, and Jimmy. Background Information. Retrovirus Viruses that copy RNA into DNA HIV is a lentrivirus , a subset of retroviruses. They are slow viruses, meaning there is an interval between infection and the onset of symptoms.

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The Effect of HIV on the Immune System

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  1. The Effect of HIV on the Immune System Rico, Patrick, Myeong Jin, and Jimmy

  2. Background Information • Retrovirus • Viruses that copy RNA into DNA • HIV is a lentrivirus, a subset of retroviruses. • They are slow viruses, meaning there is an interval between infection and the onset of symptoms. • HIV can always turn into AIDS, what differs in each patient is the time it takes.

  3. Reverse Transcriptase • The process of changing the viral RNA into a complementary DNA sequence. • The viral DNA then joins with the cell DNA, and integrates the virus into the cell. • The DNA then produces viral proteins, resulting in more HIV cells to infect the rest of the cells in the infected body.

  4. HIV in the Bloodstream • Using the process of reverse transcriptase, HIV travels through the infected body infecting CD4+T cells. • T cells are responsible for helping B cells in make antibodies or killing foreign cells aside from bacteria. • The HIV infection makes the T cells useless, as well as using them to reproduce and infect other T Cells. • A healthy human has over 1,000 T cells, someone with HIV can have less than 200.

  5. Effect on the Immune System

  6. Bibliography • Arnold, Eddy. Reverse Transcriptase. Digital image. Nature.com. Nature Publishing Group, 8 May 2008. Web. 30 Sept. 2009. <http://www.nature.com/nature/journal/v453/n7192/images/453169b-f1.2.jpg>. • Burrell, John. "Defense Against Infectious Disease." Click4Biology. 31 Aug. 2009. Web. 30 Sept. 2009. <http://click4biology.info/c4b/6/hum6.3.htm#seven>. • HIV Anatomy. Digital image. Mpelembe Network. Mpelembe Network, 6 Jan. 2006. Web. 28 Sept. 2009. <http://mpelembe.blogware.com/_photos/ZYGOTE-MEDIA-GROUP-HIV-ANAT.jpg>. • "HIV Infection: Reverse Transcription." CELLS Alive!QuillGraphics, 2006. Web. 30 Sept. 2009. <http://www.cellsalive.com/hiv2.htm>. • "What are CD4+T Cells?" HIV.com. WebMagic, Inc., 2000. Web. 30 Sept. 2009. <http://www.hiv.com/page5.html>.

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