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VACCINOLOGY

VACCINOLOGY. JEOPARDY!. 2010. Concepts. Facts. Application. Definitions. Tie- Breakers. 100. 100. 100. 100. 100. 200. 200. 200. 200. 200. 300. 300. 300. 300. 300. 400. 400. 400. 400. 400. 500. 500. 500. 500. 500. 1-1-Q.

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VACCINOLOGY

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  1. VACCINOLOGY JEOPARDY! 2010

  2. Concepts Facts Application Definitions Tie- Breakers 100 100 100 100 100 200 200 200 200 200 300 300 300 300 300 400 400 400 400 400 500 500 500 500 500

  3. 1-1-Q Antibodies can be produced against almost any substance… TRUE OR FALSE?

  4. 1-1-A TRUE

  5. 1-2-Q The more similar a vaccine is to the natural pathogen, the better the immune response to the vaccine… TRUE OR FALSE?

  6. 1-2-A TRUE

  7. 1-3-Q All vaccines present modified/selected antigen(s) that induce an immune response without causing INFECTION… TRUE OR FALSE?

  8. 1-3-A FALSE

  9. 1-4-Q Humoral and cell-mediated immune responses CANNOT occur at the same time… TRUE OR FALSE?

  10. 1-4-A FALSE FALSE

  11. 1-5-Q Which of the following statements are true of acquired, but not innate immunity? (a) Involves cytokines and complement (b) Can be induced by vaccine (c) Key mechanism is to prevent injury and death from infection (d) Gets stronger over time 1. a and c 2. b and d 3. a, b, and c

  12. 1-5-A 2. b and d

  13. 2-1-Q Some antibodies coat organisms, making them more readily ingested by phagocytes… TRUE OR FALSE?

  14. 2-1-A TRUE

  15. 2-5-Q T-cell independent responses usually produce immunological memory? TRUE OR FALSE?

  16. 2-5-A FALSE

  17. 2-4-Q B* B B* IgM • What type of response is depicted here? • T-cell independent • T-cell dependent

  18. 2-4-A • T-cell independent

  19. 2-3-Q Factors that affect the immune response include: (a) Route of vaccine administration (b) Presence of maternal antibody (c) Characteristics of the antigen (d) Host’s nutritional status 1. b, c, and d 2. b and c 3. a, b, c, and d

  20. 2-3-A 3. a, b, c & d

  21. 2-2-Q Daily Double Functions of the complement system include: (a) cell lysis (b) attracting phagocytes to the site of inflammation (c) coating antigens to make them more susceptible to phagocytosis (d) promoting inflammation 1. a, b, c, & d 2. a, b & c 3. a & d

  22. 2-2-A 1. a, b, c & d

  23. 3-3-Q Interruption of a series of vaccinations does not require starting the series over again, regardless of the interval elapsed. TRUE OR FALSE?

  24. 3-3-A TRUE

  25. 3-1-Q If two live parenteral vaccines are given 14 days apart, the vaccine that was given first should be repeated 28 days later. TRUE OR FALSE?

  26. 3-1-A FALSE

  27. 3-4-Q A live oral vaccine and a live injectable vaccine must be administered on the same day or one month apart. TRUE OR FALSE?

  28. 3-4-A FALSE

  29. 5-4-Q What vaccines should NOT be given to a perinatally HIV-infected toddler with a normal CD4 count and no history of opportunistic infections? (a) MMR (b) Varicella (c) Hepatitis B (d) Pneumococcal Conjugate 1. b 2. a and b 3. None of the above

  30. 5-4-A 3. None of the above

  31. 5-1-Q If a person will be having a splenectomy in 2 week’s time, it is too late to immunize them with the recommended vaccines. TRUE OR FALSE?

  32. 5-1-A FALSE

  33. 4-5-Q The immunoglobulin that predominates in the secondary immune response (a) IgM (b) IgG (c) IgA (d) IgE

  34. 4-5-A (b) IgG

  35. 4-4-Q This type of vaccine stimulates B cells without the help of T cells (a) Conjugated polysaccharide vaccine (b) Pure polysaccharide vaccine (c) Recombinant vaccine

  36. 4-4-A (b) Pure polysaccharide vaccine

  37. 4-1-Q Lymphocytes that mediate cell-mediated immunity are called ... (a) T-lymphocytes (b) B-lymphocytes (c) T4 lymphocytes

  38. 4-1-A (a) T-lymphocytes

  39. 4-2-Q These are non-antibody proteins that function as chemical messengers that regulate all immune responses. (a) Antigen-presenting cells (APCs) (b) Cytokines (c) Complement

  40. 4-2-A (b) Cytokines

  41. 4-3-Q Daily Double A cascade of blood proteins that can destroy foreign or infected cells. (a) Interleukins (b) Complement (c) Natural killer cells

  42. 4-3-A (b) Complement

  43. 3-2-Q Vaccine doses given at less than the recommended interval may result in less than optimal antibody response and should not be counted as part of a primary series. TRUE OR FALSE?

  44. 3-2-A TRUE

  45. 3-5-Q Simultaneous administration of a passive immunizing agent (E.g. immune globulin) and an inactivated vaccine is not recommended for post exposure prophylaxis. TRUE OR FALSE?

  46. 3-5-A FALSE

  47. 5-3-Q Inactivated vaccines are not likely to be affected by circulating maternal antibodies. TRUE OR FALSE?

  48. 5-3-A TRUE

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