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UNC Medical Image Analysis Group

UNC Medical Image Analysis Group. Who are we. UNC Facilities for Medical Imaging & Analysis. A Computer Science Graphics & Image Lab (Pizer, Gerig, Styner) B RadOnc Computorium (Joshi) Ca Neuroimage Analysis Lab NIRL (fMRI, EPR: Belger) Neurolab (sMRI, DTI: Gerig, Styner)

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UNC Medical Image Analysis Group

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  1. UNC Medical Image Analysis Group

  2. Who are we

  3. UNC Facilities for Medical Imaging & Analysis • A Computer Science Graphics & Image Lab (Pizer, Gerig, Styner) • B RadOnc Computorium (Joshi) • Ca Neuroimage Analysis Lab • NIRL (fMRI, EPR: Belger) • Neurolab (sMRI, DTI: Gerig, Styner) • NDRC (Belger, Gerig, Styner) • Cb Neurosurgical Planning Lab • D Radiology CADDLAB (Aylward) • E TEACH Autism Satellite Lab • F UNC Radiology (MRI, US) • G Duke BIAC (fMRI, MRI, MRS) • H Duke Radiology (CAMRAD) G,H F E

  4. Faculty Guido Gerig (CS & Psych) Martin Styner (CS & Psych) Stephen M. Pizer (CS) Stephen Aylward (Radiol) Sarang Joshi (RadOnc) Elizabeth Bullitt (Surgery) Mark Foskey (RadOnc) Joseph Piven (Psych) John H. Gilmore (Psych) Diana Perkins (Psych) Aysenil Belger (Psych) Heather Cody (Psych) Weili Lin (Radiol UNC) Gregory McCarthy (BIAC) Senior Res. Staff Joseph Blocher Sampath Vetsa Isabelle Corouge Matthieu Jomier Joshua Bizzell Students Ipek Oguz Casey Goodlett > 25 Graduate Students Others Technical Assistants: 4 Guest students: 9 Trainees: 3 Who are we – people

  5. UNC Neuroimaging Research Projects • Schizophrenia Research • Neonatal Study: Infants at Risk • Prodromal (subjects at risk) • First Episode FE (>250 scans, longitudinal) • Schizo-affected adolescents(TAPS) • Treatment Studies (CHOR, CATIE) • Pharmaceutical treatment study (Eli Lilly HGDG, >750 scans, longitudinal) • Autism / Fragile-X (w. Stanford) (longitudinal design, 2 to 4 years, >130 scans) • Twin Study / Sibling Study • Neurodevelopment Research Center NDRC • Surgical Planning: Tumor & Vascularity • Neonatal screening by 3D ultrasound & processing (>200 3D scans) • Neonate MRI study (babies at risk, longitudinal design, MRI&DTI, >120 scans) • Neonatal twin study (heritability) • ….

  6. Grant funding • P20 Medical Image Presentation MIP • P50 Silvio Conte Center • U54 Autism STAART Center • U54 NAMIC (15%) • P30 Neurodevelopmental Disorders Research Core NDRC • > 10 R01s related to neuroimaging research • External: NAAR, Eli Lilly etc. • ….

  7. How do we fit with NAMIC • UNC Neuroimaging has profound experience with methodology development driven by clinical projects: • Joint collaboration CS and clinical partners • Tools validated, tested and applied in large clinical projects • Training & education is/was always critical part • UNC Neuroimaging Lab has profound experience with ITK-based open-source SW development: • UNC original ITK developer’s site (Aylward, Ibanez, Jomier etc.) • SNAP-ITK, ValMet, DTItools, Imagine, MRIwatcher, …. • Use our UNC experience with large clinical studies in collaborations with Core 3 groups • Contributions: Algorithms for DTI, Shape, Statistics, Segmentation etc.

  8. How does NAMIC help us • Closes important gap difficult to fund otherwise: • Methods at the frontiers professionally implemented, transferred to clinical partners and rigorously tested and compared • NAMIC Toolkit: UNC tools become available and are promoted: • Unique chance for testing, validation, feedback, competitive comparison • NAMIC provides professional SW environment: • Amplifies UNC-focused projects, reach out • Collaborative R&D effort makes science stronger • NAMIC extremely attractive for GRAs/PostDocs: • Get exposed to multi-site multi-disciplinary effort • Collaborate with students of other labs and end-users • Learn importance of structured/professional prototyping and programming: Efficiency, time-to-market, importance of testing

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