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MANUAL on ALERT ORGANISM SURVEILLANCE

MANUAL on ALERT ORGANISM SURVEILLANCE. Infection Control Unit Quality in Medical Care Section Medical Development Division Ministry of Health Malaysia. Surveillance.

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MANUAL on ALERT ORGANISM SURVEILLANCE

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  1. MANUAL on ALERT ORGANISM SURVEILLANCE Infection Control Unit Quality in Medical Care Section Medical Development Division Ministry of Health Malaysia

  2. Surveillance Surveillance is defined as the systematic active collecting, consolidating, and analyzing data concerning the distribution and determinants of a given disease or event, followed by dissemination of that information to those who can change the results.

  3. Introduction to Alert Organism Surveillance Manual • Surveillance is an essential component of the prevention and control of infection in hospitals. • It helps to identify risks of infection and reinforces the need for good practices. • Preventing outbreak depends on prompt recognition of an infection and instituting control measure to reduce the spread of infection.

  4. Introduction to Alert Organism Surveillance Manual • Collection of accurate data allows comparison with other units or institutions and measurement of response to changes in practice. • It consists of routine collection of data on infection among patients or staff, analysis and the dissemination of the result so that appropriate action can be implemented.

  5. Cont - Introduction • Alert organism surveillance is the continuous active monitoring of the incidence of specified organisms of clinical interests. • It is laboratory based surveillance. All laboratories shall use a standard definition for identification and reporting of these alert organisms (See Appendix 1). • This surveillance program measures both healthcare associated infection and colonization attributed to the alert organism of interest.

  6. Infection • A positive culture from a sterile site (blood, CSF, pleural fluid, peritoneal fluid) unless determined to be contaminant OR • A positive culture for the selected organisms isolated from a non-sterile site isolate AND presence of clinical signs and symptoms OR determined by attending physician

  7. Colonization Colonization means the presence of microorganisms on skin, mucous membranes, open wounds, or excretions or secretions but is not causing adverse clinical signs or symptoms. Contamination Presence of microorganisms that do not multiply or cause clinical problems

  8. Objectives • The objective of alert organism surveillance program is to determine the rate and trend of specified alert organisms in all hospitals in Malaysia using standardized laboratory and clinical criteria. • This is essential for prevention and early detection of outbreak and timely investigation and institution of control measures.

  9. Methodology Population under surveillance • The population under surveillance is all inpatients. Exclusion criteria; • Cases from Emergency department, clinic, or other outpatient services • Cases previously identified at other acute care facilities/hospitals • Cases re-admitted with same alert organisms within one year • Screening culture

  10. Cont - Methodology The alert organisms under surveillance are: • Methicillin-resistant S. aureus(MRSA) • Extended Spectrum Beta Lactamases (ESBL) producing Klebsiellapneumoniae • Extended Spectrum Beta Lactamases (ESBL) producing Escherichia coli • Multidrug resistant Acinetobacterbaumanii • Carbapenem resistant Enterobacteriaceae (CRE)

  11. Methodology - Case definitions • Alert organism case definition must fulfill all three criteria; • Isolation of an alert organism from any body sites • The patient must be admitted to the ward • The case must be “Newly Identified”

  12. Methodology - Case definitions “Newly identified” include: • Alert organism identified for the first time during current hospital admission • Cases that have been identified at your site but are new case. This means that the patient was exposed and acquired another new infection

  13. Cont - Methodology NOTE: • If more than one type of alert organisms were isolated from the same patient, they should be counted separately • If a colonized case subsequently develop an infection, the case is counted as a new infection

  14. ALERT ORGANISMS Alert organisms are identified in microbiology laboratory and include organisms such as MRSA and other antibiotic resistant organisms

  15. ALERT ORGANISMS - MRSA • MRSA - Staphylococcus aureus that tests oxacillin- or cefoxitin-resistant by standard susceptibility testing methods; or by a positive result for penicillin binding protein 2a (PBP2a) latex agglutination test or molecular testing for mecA gene. • May also include positive results of specimens tested by other validated polymerase chain reaction (PCR) tests for MRSA.

  16. ALERT ORGANISMS - ESBL • ESBL - are enzymes that mediate resistance to extended-spectrum (third generation) cephalosporins (e.g., ceftazidime, cefotaxime, and ceftriaxone) and monobactams (e.g., aztreonam). • CLSI recommends confirmation of potential ESBL-producing isolates of K. pneumoniaeor and E. coli  by performing phenotypictesting using both cefotaxime and ceftazidime, alone and in combination with clavulanic acid.

  17. ALERT ORGANISMS MDR - Acinetobacterspp. Acinetobacterbaumanii (resistant or intermediate) to three or more antimicrobial classes.

  18. ALERT ORGANISMS Carbapenem resistant Enterobacteriaceae Enterobacteriaceae that meet the following criteria; Intermediate or resistant to imipenem, meropenem, ertapenem or doripenem using MIC method and confirmed by molecular method

  19. Data Collection • Infection Control Personnel (ICP) shall collects data on alert organism on a daily basis from the laboratory. • The ICP will liaise with staff in the relevant clinical area to ensure that the infection control practices are implemented. • Where appropriate, the Clinical Microbiologist or Scientific Officer will inform the relevant Clinician of the result.

  20. Cont - Data Collection • Upon isolation of Alert Organisms, the ICP should investigate and complete the Alert Organism Surveillance Form (Appendix 2) and Line-listing Form (Appendix 3). • The specific type of infection is determined based on the CDC/NHSN Surveillance Definition of Healthcare-Associated Infection and Criteria for Specific Types of Infections in the Acute Care Setting. • The classification of infection in relation to the health care facility is detailed in Appendix 4.

  21. ALERT ORGANISM SURVEILLANCE FORM MINISTRY OF HEALTH MALAYSIA MDRO/KKM/2012/1 Appendix 2

  22. Appendix 3 LINE LISTING FORM

  23. Classification Of Infection In Relation To The Healthcare Facility Appendix 4

  24. Data Analysis And Reporting • The inpatient data will be used as denominators to calculate the incidence rate of alert organisms in each hospital. • Following data will be collected: • Total number of hospital admissions • Total number of patient days (to collect 12 midnight statistics from Record Office)

  25. Data Analysis And Reporting • Cont- Data Analysis And Reporting • All hospitals shall send the aggregated data on monthly basis to the State Coordinator using Appendix 5. • The state Infection Control Coordinator shall then send the compiled data to the Infection Control Unit, Quality in Medical Care Section, MOH.

  26. Data Analysis And ReportingData Analysis And Reporting • Cont - Data Analysis And Reporting • The data will be analyzed and result will be disseminated every 6-monthly. • A yearly report will be published which will include; • Incidence of each healthcare-associated alert organisms per 100 admissions • Incidence of each healthcare-associated alert organisms per 1,000 patient-days

  27. Cont - Data Analysis And Reporting RATES: • Total no. of HCAI cases x 100 Total admission of the month 2. Total no. of HCAI cases x 1000 Total patient days for the month

  28. Patient Days • Patient days are the total number of days that patients are in the location during the selected time period. • Example: ten patients were in the unit on the 1st day of the month; 12 on day 2; 11 on day 3; 13 on day 4; 10 on day 5; 6 on day 6; and 10 on day 7; and so on. If we counted the patients in the unit from day 1 through 7, we would add 10+12+11+13+10+6+10 for a total of 72 patient days for the 1st week of the month. If we continued for the entire month, the number of patient days for the month is simply the sum of the daily counts.

  29. VERIFIED BY: Name: Designation: Date: REPORTED BY: Name: Designation: Date:

  30. Isolate of Alert Organism Clinical Microbiologist/ Scientific Officer informs the result to Clinician where appropriate ICP collects data on daily basis from the laboratory Complete the Alert Organism SurveillanceForm (Appendix 2) and the Line Listing (Appendix 3) Classify the infection according to types and its relation to healthcare facility Analyse the data at the end of the month and complete Monthly Alert Organism Reporting Form (Appendix 5) to get the rate of infection for each type of alert organism

  31. Prepare report using Ms EXCEL/ (SPCC) and submit to HIACC Chairman • Submit Monthly Alert Organism Reporting Form (Appendix 5)to the State Coordinator for compilation by 10th of every month • State Coordinator to submit the compiled report to Infection Control Unit, Medical Development Division, MOH by 20th of every month • Data management by the National Secretariat

  32. THANK YOU

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